ID	SACE_0723	Type	CDS
From	800023	nt length	10704
To	810726	aa length	3567
Gene	eryAII	pI	4.67
Definition	EryAII Erythromycin polyketide synthase modules 3 and 4	M.W (Da)	374363
Note		AseI frg.	B
SignalP v.4.0	Non-secretory protein | plot	Category

Orthologs (if any)

Pfam search result

	Model	No.	Description	Position (aa)	Score	E-value
	Acyl_transf_1	2	Acyl transferase domain	560-880, 2015-2331	686.0	7.3e-207
	ketoacyl-synt	2	Beta-ketoacyl synthase, N-terminal domain	31-280, 1489-1739	582.1	1e-175
	Ketoacyl-synt_C	2	Beta-ketoacyl synthase, C-terminal domain	288-405, 1747-1862	292.2	2e-88
	KR	2	KR domain	1132-1297, 3141-3317	278.2	2.5e-83
	PS-DH	1	Polyketide synthase dehydratase	2377-2645	150.5	5.3e-44
	KAsynt_C_assoc	2	Ketoacyl-synthetase C-terminal extension	408-523, 1867-1977	130.9	2.3e-38
	Erythro-docking	1	Erythronolide synthase, docking	3490-3547	117.4	1.6e-34
	PP-binding	2	Phosphopantetheine attachment site	1400-1466, 3424-3484	89.5	1.2e-25
	ADH_zinc_N	1	Zinc-binding dehydrogenase	2969-3063	58.1	7.5e-16
	ADH_zinc_N_2	1	Zinc-binding dehydrogenase	3006-3131	56.2	6.6e-15
	Thiolase_N	1	Thiolase, N-terminal domain	1649-1700	52.5	3.9e-14
	adh_short	1	short chain dehydrogenase	3142-3298	51.3	8.6e-14
	Epimerase	1	NAD dependent epimerase/dehydratase family	3143-3276	43.9	1.7e-11
	ADH_N	1	Alcohol dehydrogenase GroES-like domain	2851-2905	29.6	4.5e-07
	Docking	1	Erythronolide synthase docking	3-27	28.9	5.6e-07

BLAST search result (top 10 hits)

ID	Description	Score	E-value
WP_011873138.1	erythronolide synthase [Saccharopolyspora erythraea] >gb	16214	0.0e+00
CAA44448.1	6-deoxyerythronolide B synthase II [Saccharopolyspora erythraea ...	16211	0.0e+00
WP_081494992.1	hypothetical protein [Saccharopolyspora erythraea]	16209	0.0e+00
Q03132.3	RecName: Full=6-deoxyerythronolide-B synthase EryA2, modules 3 and ...	16193	0.0e+00
WP_050784278.1	type I polyketide synthase [Saccharopolyspora erythraea]	12513	0.0e+00
AAG13918.1	megalomicin 6-deoxyerythronolide B synthase 2 [Micromonospora meg...	11935	0.0e+00
AIS23784.1	polyketide synthase, partial [Actinopolyspora erythraea]	11416	0.0e+00
ANZ15338.1	Erythronolide synthase, modules 3 and 4 [Streptomyces noursei ATC...	9725	0.0e+00
WP_067345569.1	hypothetical protein [Streptomyces noursei]	9722	0.0e+00
WP_051850753.1	type I polyketide synthase [Streptomyces griseofuscus]	9044	0.0e+00

PSORT result

Localization	Certainty	PSORT said
Not Clear

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