| ID | SAVERM_1022
| Type | CDS
|
| From | 1289024
| nt length | 1242
|
| To | 1290265
| aa length | 413
|
| Gene | crtE
| pI | 7.83
|
| Definition | geranylgeranyl diphosphate synthase
| M.W (Da) | 43532
|
| Note | crt gene cluster, probably geranylgeranyl pyrophosphate synthase, PF00348: Polyprenyl synthetase
| AseI frg. | A
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | antibiotic production
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO0185 putative geranylgeranyl pyrophosphate synthase | 234 | 3.0e-74
|
| sgr | SGR_7079t putative geranylgeranyl pyrophosphate synthase | 330 | 3.0e-111
|
| sam | SAM23877_7080 putative geranylgeranyl pyrophosphate synthase | 289 | 2.0e-95
|
| scab | SCAB5461 polyprenyl diphosphate synthase | 462 | 2.0e-162
|
| sace | SACE_1714 geranylgeranyl pyrophosphate synthase | 249 | 2.0e-80
|
| nfar | nfa17390 polyprenyl synthase | 246 | 2.6e-66
|
| mtub | gi|15609310 PROBABLE GERANYLGERANYL PYROPHOSPHATE SYNTHETASE IDSA2 (GGPPSASE) (GGPP SYNTHETASE) (GERANYLGERANYL DIPHOSPHATE SYNTHASE) [Mycobacterium tuberculosis H37Rv] | 207 | 1.0e-54
|
| cglu | gi|19553374 COG0142:Geranylgeranyl pyrophosphate synthase [Corynebacterium glutamicum] | 211 | 5.9e-56
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| polyprenyl_synt | 1 | Polyprenyl synthetase | 63-304 | 163.9 | 3.2e-48
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_079141636.1 | polyprenyl synthetase family protein [Streptomyces sp. LUP30...
| 1049 | 2.0e-137 |
| WP_109003977.1 | polyprenyl synthetase family protein [Streptomyces rishirien...
| 1023 | 1.5e-133 |
| GGR76397.1 | geranylgeranyl pyrophosphate synthase [Streptomyces humidus]
| 1017 | 8.0e-133 |
| WP_190148401.1 | polyprenyl synthetase family protein [Streptomyces humidus]
| 1016 | 1.7e-132 |
| WP_148011585.1 | polyprenyl synthetase family protein [Streptomyces sp. me109...
| 1003 | 1.7e-130 |
| WP_237312592.1 | polyprenyl synthetase family protein [Streptomyces sp. AMCC4...
| 1000 | 2.0e-130 |
| WP_045561226.1 | polyprenyl synthetase family protein [Streptomyces sp. Fxana...
| 999 | 3.1e-130 |
| WP_086800213.1 | polyprenyl synthetase family protein [Streptomyces caniscabi...
| 999 | 3.7e-130 |
| WP_193379693.1 | polyprenyl synthetase family protein [Streptomyces caniscabi...
| 998 | 4.6e-130 |
| OQR63122.1 | geranylgeranyl pyrophosphate synthase [Streptomyces sp. B9173]
| 997 | 7.0e-130 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.0919 | Seems to have no N-terminal signal seq.
|