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IDSAVERM_1038 TypeCDS
From1313665 nt length945
To1312721 aa length314
GenehemC2 pI5.84
Definitionputative porphobilinogen deaminase M.W (Da)33545
NotePF01379: Porphobilinogen deaminase, dipyromethane cofactor binding domain AseI frg.A
SignalP v.4.0Non-secretory protein | plot Categorymetabolism of coenzymes & prosthetic groups


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO7343 porphobilinogen deaminase.5380.0e+00
samSAM23877_0864 Porphobilinogen deaminase 25380.0e+00
scabSCAB7581 putative porphobilinogen deaminase5150.0e+00
bsubBG10342 hemC; porphobilinogen deaminase (hydroxymethylbilane synthase) [EC:4.3.1.8]2091.7e-55
ecoligi|49176416 porphobilinogen deaminase [Escherichia coli K12]2021.8e-53
paerPA5260 [gene=hemC] [prot=porphobilinogen deaminase] [comment=PA5260]1931.9e-50

*coel, Streptomyces coelicolor A3(2); sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

Porphobil_deam1Porphobilinogen deaminase, dipyromethane cofactor binding domain10-216210.61.6e-62

Porphobil_deamC1Porphobilinogen deaminase, C-terminal domain232-30146.53.2e-12

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
EKX66843.1 hydroxymethylbilane synthase [Streptomyces ipomoeae 91-03] 13150.0e+00
WP_048820183.1 hydroxymethylbilane synthase [Streptomyces ipomoeae] >lcl 13048.1e-180
WP_144315490.1 hydroxymethylbilane synthase [Streptomyces sp. RLB3-17] >gb 12934.2e-178
WP_054230788.1 MULTISPECIES: hydroxymethylbilane synthase [Streptomyces] >g... 12925.4e-178
WP_189786132.1 hydroxymethylbilane synthase [Streptomyces capitiformicae] >... 12873.4e-177
WP_153290468.1 hydroxymethylbilane synthase [Streptomyces fagopyri] >gb 12848.1e-177
WP_168491765.1 MULTISPECIES: hydroxymethylbilane synthase [Streptomyces] >g... 12821.5e-176
WP_189768724.1 hydroxymethylbilane synthase [Streptomyces tauricus] >dbj 12812.8e-176
WP_149828153.1 hydroxymethylbilane synthase [Streptomyces tailanensis] 12803.1e-176
WP_107014963.1 MULTISPECIES: hydroxymethylbilane synthase [Streptomyces] >l... 12804.0e-176

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.1223 Seems to have no N-terminal signal seq.