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IDSAVERM_1934 TypeCDS
From2365934 nt length1467
To2364468 aa length488
GenealkA1 pI9.12
Definitionputative ADA-like regulatory protein M.W (Da)53033
NotePF06029: AlkA N-terminal domain AseI frg.C
SignalP v.4.0Non-secretory protein | plot Categoryregulation


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO6461 putative ADA-like regulatory protein8220.0e+00
sgrSGR_1201 putative ADA-like transcriptional regulator7410.0e+00
samSAM23877_6055 putative bifunctional transcriptional activator/DNA repair enzyme AlkA8250.0e+00
scabSCAB17791 putative ADA-like regulatory protein8130.0e+00
saceSACE_3676 putative ADA-like regulatory protein6920.0e+00
nfarnfa47900 alkA 3-methyladenine DNA glycosylase4761.5e-135
mtubgi|15608457 PROBABLE ADA REGULATORY PROTEIN ALKA (Regulatory protein of adaptative response) (Methylated-DNA--protein-cysteine methyltransferase) (O-6-methylguanine-DNA alkyltransferase) (O-6-methylguanine-DNA methyltransferase) (3-methyladenine DNA glycosylase II) [Mycobacterium tuberculosis H37Rv]6206.2e-179
bsubBG10165 alkA; DNA-3-methyladenine glycosidase [EC:3.2.2.21]824.1e-17
ecoligi|16130008 3-methyl-adenine DNA glycosylase II, inducible [Escherichia coli K12]1301.9e-31
paerPA1686 [gene=alkA] [prot=DNA-3-methyladenine glycosidase II] [comment=PA1686]1832.7e-47

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

AlkA_N1AlkA N-terminal domain198-313111.23.1e-32

Ada_Zn_binding1Metal binding domain of Ada8-7190.83.8e-26

HTH_181Helix-turn-helix domain106-18565.14.7e-18

HhH-GPD1HhH-GPD superfamily base excision DNA repair protein319-46827.23.8e-06

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_071368299.1 helix-turn-helix domain-containing protein [Streptomyces col... 19600.0e+00
WP_144316555.1 helix-turn-helix domain-containing protein [Streptomyces sp.... 19470.0e+00
WP_199839197.1 helix-turn-helix domain-containing protein [Streptomyces sp.... 19290.0e+00
WP_220296382.1 helix-turn-helix domain-containing protein [Streptomyces sp.... 19280.0e+00
KUJ38890.1 DNA-3-methyladenine glycosylase [Streptomyces sp. NRRL F-5122] 19280.0e+00
WP_185124254.1 helix-turn-helix domain-containing protein [Streptomyces sp.... 19260.0e+00
WP_199827453.1 helix-turn-helix domain-containing protein [Streptomyces xyl... 19240.0e+00
WP_199931981.1 helix-turn-helix domain-containing protein [Streptomyces sp.... 19230.0e+00
WP_189900097.1 helix-turn-helix domain-containing protein [Streptomyces spi... 19220.0e+00
WP_095751197.1 helix-turn-helix domain-containing protein [Streptomyces sp.... 19220.0e+00

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.0495 Seems to have no N-terminal signal seq.