| ID | SAVERM_2046
| Type | CDS
|
| From | 2496389
| nt length | 2319
|
| To | 2498707
| aa length | 772
|
| Gene | metE
| pI | 5
|
| Definition | putative 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
| M.W (Da) | 83151
|
| Note | PF01717: Methionine synthase, vitamin-B12 independent
| AseI frg. | C
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of amino acids & related molecules
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO0985 putative methionine synthase | 1293 | 0.0e+00
|
| sgr | SGR_1212 putative methionine synthase | 1289 | 0.0e+00
|
| sace | SACE_4744 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase | 852 | 0.0e+00
|
| nfar | nfa52280 metE methionine synthase | 687 | 0.0e+00
|
| mtub | gi|15608273 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [Mycobacterium tuberculosis H37Rv] | 845 | 0.0e+00
|
| cglu | gi|19552365 COG0620:Methionine synthase II (cobalamin-independent) [Corynebacterium glutamicum] | 649 | 0.0e+00
|
| bsub | BG12616 metC; cobalamin-independent methionine synthase [EC:2.1.1.14] | 615 | 3.8e-177
|
| ecoli | gi|16131678 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [Escherichia coli K12] | 716 | 0.0e+00
|
| paer | PA1927 [gene=metE] [prot=5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase] [comment=PA1927] | 729 | 0.0e+00
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| Meth_synt_2 | 1 | Cobalamin-independent synthase, Catalytic domain | 441-763 | 495.6 | 6e-149
|
| Meth_synt_1 | 1 | Cobalamin-independent synthase, N-terminal domain | 13-323 | 400.8 | 4.3e-120
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
|
| 3261 | 0.0e+00 |
| QIY94361.1 | 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltrans...
| 3253 | 0.0e+00 |
|
| 3244 | 0.0e+00 |
| WP_019071130.1 | 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyl...
| 3239 | 0.0e+00 |
| WP_067378718.1 | 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyl...
| 3238 | 0.0e+00 |
|
| 3238 | 0.0e+00 |
| WP_143607504.1 | MULTISPECIES: 5-methyltetrahydropteroyltriglutamate--homocys...
| 3237 | 0.0e+00 |
| WP_181652305.1 | 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyl...
| 3236 | 0.0e+00 |
| WP_125214943.1 | 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyl...
| 3233 | 0.0e+00 |
| WP_093629949.1 | 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyl...
| 3232 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.3963 | Seems to have no N-terminal signal seq.
|