| ID | SAVERM_2079 | Type | CDS |
| From | 2532463 | nt length | 1743 |
| To | 2530721 | aa length | 580 |
| Gene | poxB2 | pI | 7.4 |
| Definition | putative pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors | M.W (Da) | 62535 |
| Note | PF02776: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain | AseI frg. | C |
| SignalP v.4.0 | Non-secretory protein | plot | Category | main glycolytic pathways |
| Bacteria* | Reciprocally best hit to | Score | E-value |
| coel | SCO6155 pyruvate dehydrogenase | 1062 | 0.0e+00 |
| sgr | SGR_1364 putative pyruvate dehydrogenase | 1048 | 0.0e+00 |
| sam | SAM23877_5870 pyruvate dehydrogenase (pyruvate oxidase), thiamin-dependent, FAD-binding | 1057 | 0.0e+00 |
| sace | SACE_1218 pyruvate dehydrogenase | 770 | 0.0e+00 |
| cglu | gi|19553809 COG0028:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Corynebacterium glutamicum] | 674 | 0.0e+00 |
| ecoli | gi|16128839 pyruvate dehydrogenase [Escherichia coli K12] | 615 | 3.2e-177 |
| paer | PA5297 [gene=poxB] [prot=pyruvate dehydrogenase (cytochrome)] [comment=PA5297] | 471 | 6.0e-134 |
| Model | No. | Description | Position (aa) | Score | E-value | |
| TPP_enzyme_N | 1 | Thiamine pyrophosphate enzyme, N-terminal TPP binding domain | 5-171 | 158.7 | 9.4e-47 | |
| TPP_enzyme_C | 1 | Thiamine pyrophosphate enzyme, C-terminal TPP binding domain | 383-529 | 140.7 | 3e-41 | |
| TPP_enzyme_M | 1 | Thiamine pyrophosphate enzyme, central domain | 192-320 | 100.6 | 5.3e-29 |
| ID | Description | Score | E-value |
| WP_212726725.1 | pyruvate dehydrogenase [Streptomyces mirabilis] >gb | 2911 | 0.0e+00 |
| WP_168496950.1 | pyruvate dehydrogenase [Streptomyces sp. RLB1-33] >gb | 2908 | 0.0e+00 |
| WP_054236969.1 | MULTISPECIES: pyruvate dehydrogenase [unclassified Streptomy... | 2902 | 0.0e+00 |
| WP_055615036.1 | pyruvate dehydrogenase [Streptomyces phaeochromogenes] | 2901 | 0.0e+00 |
| QIY99024.1 | pyruvate dehydrogenase [Streptomyces sp. S1D4-11] | 2900 | 0.0e+00 |
| WP_095851945.1 | MULTISPECIES: pyruvate dehydrogenase [unclassified Streptomy... | 2900 | 0.0e+00 |
| WP_067375663.1 | pyruvate dehydrogenase [Streptomyces olivochromogenes] >gb | 2899 | 0.0e+00 |
| WP_143603297.1 | MULTISPECIES: pyruvate dehydrogenase [unclassified Streptomy... | 2898 | 0.0e+00 |
| WP_099920055.1 | pyruvate dehydrogenase [Streptomyces sp. GbtcB7] | 2897 | 0.0e+00 |
| WP_190171537.1 | pyruvate dehydrogenase [Streptomyces mirabilis] >dbj | 2897 | 0.0e+00 |
| Localization | Certainty | PSORT said |
| cytoplasm | 0.0457 | Seems to have no N-terminal signal seq. |