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IDSAVERM_2368 TypeCDS
From2893364 nt length13497
To2879868 aa length4498
Genepks5 pI5.01
Definitionputative modular polyketide synthase M.W (Da)468423
Notepks5 gene cluster, three modules AseI frg.M
SignalP v.4.0Non-secretory protein | plot Categoryantibiotic production


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO6275 putative type I polyketide synthase (fragment)33900.0e+00
sgrSGR_6179 putative type-I PKS33220.0e+00
saceSACE_4141 type I modular polyketide synthase33160.0e+00

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sace, Saccharopolyspora erythraea NRRL2338;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

ketoacyl-synt3Beta-ketoacyl synthase, N-terminal domain8-245, 975-1225, 2758-3008838.17.6e-254

Acyl_transf_13Acyl transferase domain521-832, 1531-1847, 3314-3629748.76e-226

Ketoacyl-synt_C3Beta-ketoacyl synthase, C-terminal domain254-367, 1233-1350, 3016-3133403.09e-123

PS-DH2Polyketide synthase dehydratase1895-2154, 3678-3926308.93.1e-92

KR2KR domain2382-2561, 4136-4309293.46e-88

KAsynt_C_assoc3Ketoacyl-synthetase C-terminal extension370-486, 1353-1495, 3136-3278157.01.9e-46

PP-binding3Phosphopantetheine attachment site884-949, 2668-2733, 4413-4476119.74.5e-35

Thiolase_N2Thiolase, N-terminal domain1115-1180, 2913-296376.71.7e-21

adh_short1short chain dehydrogenase2383-254255.83.7e-15

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_042492970.1 MULTISPECIES: type I polyketide synthase [Streptomyces] 202020.0e+00
KIE26574.1 polyketide synthase [Streptomyces sp. MUSC 125] 166960.0e+00
WP_052269940.1 type I polyketide synthase [Streptomyces sp. MUSC 125] 166900.0e+00
MYW40478.1 type I polyketide synthase [Streptomyces sp. SID1] 162570.0e+00
WP_014048977.1 MULTISPECIES: type I polyketide synthase [unclassified Strep... 162460.0e+00
WP_214615630.1 SDR family NAD(P)-dependent oxidoreductase [Actinomadura sp.... 146130.0e+00
WP_156217188.1 SDR family NAD(P)-dependent oxidoreductase [Actinomadura lit... 144830.0e+00
WP_145917792.1 type I polyketide synthase [Micromonospora sp. HM134] >gb 144350.0e+00
WP_194821348.1 type I polyketide synthase [Micromonospora sp. S-DT3-3-22] 144300.0e+00
OKI91982.1 hypothetical protein AMK18_32420 [Streptomyces sp. CB01249] 88080.0e+00

PSORT result

LocalizationCertaintyPSORT said
membrane0.2359 Seems to have an uncleavable N-term signal seq