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IDSAVERM_2424 TypeCDS
From2956521 nt length1086
To2955436 aa length361
GenecobW pI4.77
Definitionputative cobalamin synthesis protein M.W (Da)39377
Notecobalamin biosynthesis, PF02492: CobW/HypB/UreG, nucleotide-binding domain AseI frg.Q
SignalP v.4.0Non-secretory protein | plot Categorymetabolism of coenzymes & prosthetic groups


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO5835 hypothetical protein5360.0e+00
sgrSGR_1690 putative ATP/GTP-binding protein4323.0e-152
samSAM23877_5540 ATP/GTP-binding protein5530.0e+00
scabSCAB24301 putative cobalamin synthesis protein5360.0e+00
saceSACE_3297 cobalamin synthesis protein3463.0e-119
nfarnfa43200 cobalamin synthesis protein3131.9e-86
cglugi|19551922 COG0523:Putative GTPases (G3E family) [Corynebacterium glutamicum]1052.5e-24
bsubBG12021 yciC; probable zinc transport system permease protein1092.2e-25
ecoligi|49176496 putative synthesis protein [Escherichia coli K12]701.3e-13
paerPA2945 [gene=PA2945] [prot=conserved hypothetical protein] [comment=PA2945]1195.6e-28

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

cobW1CobW/HypB/UreG, nucleotide-binding domain11-184149.65.9e-44

CobW_C1Cobalamin synthesis protein cobW C-terminal domain233-32278.62.4e-22

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
PIB06317.1 cobalamin biosynthesis protein CobW [Streptomyces sp. HG99] 13990.0e+00
WP_099504011.1 MULTISPECIES: GTP-binding protein [Streptomyces] >gb 13980.0e+00
WP_168496442.1 MULTISPECIES: GTP-binding protein [Streptomyces] >gb 13930.0e+00
QIY98744.1 GTP-binding protein [Streptomyces sp. S1D4-11] 13920.0e+00
GHD66778.1 cobalamin biosynthesis protein CobW [Streptomyces mirabilis] 13910.0e+00
WP_229889328.1 GTP-binding protein [Streptomyces mirabilis] 13890.0e+00
SFF90919.1 GTPase, G3E family [Streptomyces mirabilis] 13880.0e+00
WP_097286533.1 GTP-binding protein [Streptomyces sp. OK228] >emb 13870.0e+00
GAX53671.1 cobalamin biosynthesis protein CobW [Streptomyces olivochromogen... 13870.0e+00
WP_217566204.1 GTP-binding protein [Streptomyces sp. GbtcB7] 13850.0e+00

PSORT result

LocalizationCertaintyPSORT said
outside0.3000 Seems to have a cleavable N-term signal seq.