| ID | SAVERM_2718
| Type | CDS
|
| From | 3335649
| nt length | 1044
|
| To | 3334606
| aa length | 347
|
| Gene | leuB
| pI | 5.1
|
| Definition | putative 3-isopropylmalate dehydrogenase
| M.W (Da) | 36745
|
| Note | PF00180: Isocitrate/isopropylmalate dehydrogenase
| AseI frg. | J
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of amino acids & related molecules
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO5522 3-isopropylmalate dehydrogenase | 618 | 0.0e+00
|
| sgr | SGR_1983 putative 3-isopropylmalate dehydrogenase | 587 | 0.0e+00
|
| sam | SAM23877_5273 3-isopropylmalate dehydrogenase | 627 | 0.0e+00
|
| scab | SCAB26951 putative 3-isopropylmalate dehydrogenase | 603 | 0.0e+00
|
| sace | SACE_6154 beta-isopropylmalate dehydrogenase | 401 | 4.0e-141
|
| nfar | nfa42200 leuB isopropylmalate dehydrogenase | 453 | 1.1e-128
|
| mtub | gi|15610132 3-isopropylmalate dehydrogenase [Mycobacterium tuberculosis H37Rv] | 430 | 7.9e-122
|
| cglu | gi|19552506 COG0473:Isocitrate/isopropylmalate dehydrogenase [Corynebacterium glutamicum] | 426 | 6.1e-121
|
| bsub | BG11222 ycsA; similar to 3-isopropylmalate dehydrogenase | 237 | 8.7e-64
|
| ecoli | gi|16129754 putative tartrate dehydrogenase [Escherichia coli K12] | 258 | 5.3e-70
|
| paer | PA3118 [gene=leuB] [prot=3-isopropylmalate dehydrogenase] [comment=PA3118] | 189 | 3.2e-49
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| Iso_dh | 1 | Isocitrate/isopropylmalate dehydrogenase | 7-326 | 304.9 | 6.6e-91
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_181655648.1 | 3-isopropylmalate dehydrogenase [Streptomyces himalayensis] ...
| 1626 | 0.0e+00 |
| WP_055526121.1 | 3-isopropylmalate dehydrogenase [Streptomyces graminilatus]
| 1622 | 0.0e+00 |
| WP_181867543.1 | 3-isopropylmalate dehydrogenase [Streptomyces himalayensis] ...
| 1622 | 0.0e+00 |
| WP_067284161.1 | 3-isopropylmalate dehydrogenase [Streptomyces jeddahensis] >...
| 1622 | 0.0e+00 |
| WP_189874743.1 | 3-isopropylmalate dehydrogenase [Streptomyces bluensis] >dbj...
| 1620 | 0.0e+00 |
| WP_103838048.1 | 3-isopropylmalate dehydrogenase [Streptomyces sp. Ru72] >gb
| 1617 | 0.0e+00 |
| WP_164323030.1 | 3-isopropylmalate dehydrogenase [Streptomyces sp. SID12501] ...
| 1616 | 0.0e+00 |
| WP_131558319.1 | 3-isopropylmalate dehydrogenase [Streptomyces sp. KM273126] ...
| 1614 | 0.0e+00 |
| WP_053739826.1 | 3-isopropylmalate dehydrogenase [Streptomyces sp. NRRL WC-36...
| 1612 | 0.0e+00 |
| WP_161242332.1 | 3-isopropylmalate dehydrogenase [Streptomyces sp. SID2888] >...
| 1609 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| membrane | 0.1404 | Seems to have no N-terminal signal seq.
|