| ID | SAVERM_2730
| Type | CDS
|
| From | 3352496
| nt length | 1590
|
| To | 3350907
| aa length | 529
|
| Gene | serA
| pI | 4.7
|
| Definition | putative D-3-phosphoglycerate dehydrogenase
| M.W (Da) | 55125
|
| Note | PF02826: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
| AseI frg. | J
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of amino acids & related molecules
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO5515 serA probable D-3-phosphoglycerate dehydrogenase | 982 | 0.0e+00
|
| sgr | SGR_1997 putative D-3-phosphoglycerate dehydrogenase | 966 | 0.0e+00
|
| sam | SAM23877_5265 D-3-phosphoglycerate dehydrogenase | 984 | 0.0e+00
|
| scab | SCAB27051 putative D-3-phosphoglycerate dehydrogenase | 981 | 0.0e+00
|
| sace | SACE_6155 D-3-phosphoglycerate dehydrogenase (PgdH) | 553 | 0.0e+00
|
| nfar | nfa42210 serA D-3-phosphoglycerate dehydrogenase | 543 | 1.1e-155
|
| mtub | gi|57117042 PROBABLE D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA1 (PGDH) [Mycobacterium tuberculosis H37Rv] | 563 | 9.9e-162
|
| cglu | gi|19552504 COG0111:Phosphoglycerate dehydrogenase and related dehydrogenases [Corynebacterium glutamicum] | 523 | 8.0e-150
|
| bsub | BG10509 serA; phosphoglycerate dehydrogenase [EC:1.1.1.95] | 347 | 7.5e-97
|
| ecoli | gi|16130814 D-3-phosphoglycerate dehydrogenase [Escherichia coli K12] | 176 | 3.4e-45
|
| paer | PA3896 [gene=PA3896] [prot=probable 2-hydroxyacid dehydrogenase] [comment=PA3896] | 191 | 1.1e-49
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| 2-Hacid_dh_C | 1 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain | 109-282 | 211.0 | 7.4e-63
|
| 2-Hacid_dh | 1 | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | 7-314 | 113.3 | 6e-33
|
| ACT | 1 | ACT domain | 456-516 | 37.1 | 1.8e-09
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_202497957.1 | phosphoglycerate dehydrogenase [Streptomyces sp. SID5469]
| 2526 | 0.0e+00 |
| WP_143640587.1 | phosphoglycerate dehydrogenase [Streptomyces sp. IB201691-2A...
| 2492 | 0.0e+00 |
| QWA24301.1 | phosphoglycerate dehydrogenase [Streptomyces sp. JCM17656]
| 2490 | 0.0e+00 |
| WP_189843650.1 | MULTISPECIES: phosphoglycerate dehydrogenase [Streptomyces] ...
| 2486 | 0.0e+00 |
| WP_030948359.1 | MULTISPECIES: phosphoglycerate dehydrogenase [unclassified S...
| 2485 | 0.0e+00 |
| WP_099920522.1 | phosphoglycerate dehydrogenase [Streptomyces mirabilis] >dbj...
| 2485 | 0.0e+00 |
| WP_103838038.1 | phosphoglycerate dehydrogenase [Streptomyces sp. Ru72] >gb
| 2484 | 0.0e+00 |
| WP_055615060.1 | phosphoglycerate dehydrogenase [Streptomyces phaeochromogene...
| 2483 | 0.0e+00 |
| WP_067440209.1 | phosphoglycerate dehydrogenase [Streptomyces lincolnensis] >...
| 2483 | 0.0e+00 |
| WP_126395276.1 | phosphoglycerate dehydrogenase [Streptomyces cyaneochromogen...
| 2483 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.2355 | Seems to have no N-terminal signal seq.
|