| ID | SAVERM_2731
| Type | CDS
|
| From | 3353765
| nt length | 1002
|
| To | 3352764
| aa length | 333
|
| Gene | ilvC
| pI | 4.56
|
| Definition | ketol-acid reductoisomerase
| M.W (Da) | 36285
|
| Note | PF01450: Acetohydroxy acid isomeroreductase, catalytic domain
| AseI frg. | J
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of amino acids & related molecules
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO5514 ilvC acetolactate synthase small subunit | 617 | 0.0e+00
|
| sgr | SGR_1998 putative ketol-acid reductoisomerase | 629 | 0.0e+00
|
| sam | SAM23877_5264 Ketol-acid reductoisomerase 1 | 638 | 0.0e+00
|
| scab | SCAB27061 ketol-acid reductoisomerase | 647 | 0.0e+00
|
| sace | SACE_6157 ketol-acid reductoisomerase | 450 | 7.0e-161
|
| nfar | nfa42300 ilvC ketol-acid reductoisomerase | 454 | 4.8e-129
|
| mtub | gi|15610138 ketol-acid reductoisomerase [Mycobacterium tuberculosis H37Rv] | 447 | 3.5e-127
|
| cglu | gi|19552493 COG0059:Ketol-acid reductoisomerase [Corynebacterium glutamicum] | 412 | 1.5e-116
|
| bsub | BG10672 ilvC; ketol-acid reductoisomerase (acetohydroxy-acid isomeroreductase) [EC:1.1.1.86] | 399 | 1.6e-112
|
| ecoli | gi|16131632 ketol-acid reductoisomerase [Escherichia coli K12] | 154 | 7.9e-39
|
| paer | PA4694 [gene=ilvC] [prot=ketol-acid reductoisomerase] [comment=PA4694] | 378 | 3.5e-106
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| IlvN | 1 | Acetohydroxy acid isomeroreductase, NADPH-binding domain | 15-178 | 254.7 | 2.6e-76
|
| IlvC | 1 | Acetohydroxy acid isomeroreductase, catalytic domain | 184-327 | 212.9 | 1.9e-63
|
| F420_oxidored | 1 | NADP oxidoreductase coenzyme F420-dependent | 19-99 | 33.7 | 3.8e-08
|
| NAD_binding_2 | 1 | NAD binding domain of 6-phosphogluconate dehydrogenase | 19-104 | 29.6 | 6.5e-07
|
| 2-Hacid_dh_C | 1 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain | 15-82 | 28.1 | 1.1e-06
|
BLAST search result (top 10 hits)
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.1139 | Seems to have no N-terminal signal seq.
|