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IDSAVERM_2753 TypeCDS
From3381738 nt length1131
To3380608 aa length376
GenetrmU pI5.46
Definitionputative tRNA (5-methylaminomethyl-2-thiouridine)-methyltransferase M.W (Da)39809
NotePF03054: tRNA methyl transferase AseI frg.J
SignalP v.4.0Signal peptide | plot CategoryRNA modification

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO5488 tRNA (5-methylaminomethyl-2- thiouridylate)-methyltransferase6660.0e+00
sgrSGR_2027 putative tRNA (5-methylaminomethyl-2-thiouridine)-methyltransferase6420.0e+00
samSAM23877_5228 tRNA-specific 2-thiouridylase MnmA6590.0e+00
scabSCAB27301 putative tRNA (5-methylaminomethyl-2-thiouridine)-methyltransferase6720.0e+00
saceSACE_6187 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase4291.0e-151
nfarnfa42670 tRNA methyl transferase4361.6e-123
mtubgi|15610161 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase [Mycobacterium tuberculosis H37Rv]3976.3e-112
cglugi|19552461 COG0482:Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Corynebacterium glutamicum]3791.2e-106
bsubBG13787 trmU, yrrA; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase [EC:2.1.1.61]2114.3e-56
ecoligi|49176082 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase [Escherichia coli K12]1971.2e-51
paerPA2626 [gene=trmU] [prot=tRNA methyltransferase] [comment=PA2626]2241.3e-59

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

tRNA_Me_trans1tRNA methyl transferase12-365396.67e-119

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_184850244.1 tRNA 2-thiouridine(34) synthase MnmA [Streptomyces violaceoc... 16230.0e+00
WP_033313280.1 tRNA 2-thiouridine(34) synthase MnmA [Streptomyces iakyrus] 16220.0e+00
WP_161365969.1 tRNA 2-thiouridine(34) synthase MnmA [Streptomyces sp. SID56... 16190.0e+00
WP_107459440.1 tRNA 2-thiouridine(34) synthase MnmA [Streptomyces sp. A244]... 16170.0e+00
WP_184564575.1 tRNA 2-thiouridine(34) synthase MnmA [Streptomyces paradoxus... 16160.0e+00
WP_062929201.1 tRNA 2-thiouridine(34) synthase MnmA [Streptomyces qaidamens... 16140.0e+00
WP_030866400.1 tRNA 2-thiouridine(34) synthase MnmA [Streptomyces sp. NRRL ... 16130.0e+00
KDN73661.1 thiouridylase [Streptomyces olindensis] 16120.0e+00
WP_221755339.1 tRNA 2-thiouridine(34) synthase MnmA [Streptomyces sp. WAC04... 16110.0e+00
WP_067370870.1 tRNA 2-thiouridine(34) synthase MnmA [Streptomyces olivochro... 16110.0e+00

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.0692 Seems to have no N-terminal signal seq.