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IDSAVERM_2795 TypeCDS
From3430049 nt length1665
To3431713 aa length554
Genezmp4 pI8.71
Definitionputative griselysin (secreted neutral zinc metalloprotease) M.W (Da)57439
NotePF02868: Thermolysin metallopeptidase, alpha-helical domain AseI frg.K
SignalP v.4.0Signal peptide | plot Categoryprotein modification


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO5446 undefined product8040.0e+00
samSAM23877_5188 Neutral zinc metalloprotease8080.0e+00
scabSCAB27931 putative neutral zinc metalloprotease8090.0e+00
bsubBG10448 nprE; extracellular neutral metalloprotease [EC:3.4.24.28]1893.6e-49
paerPA3724 [gene=lasB] [prot=elastase LasB] [comment=PA3724]1712.1e-43

*coel, Streptomyces coelicolor A3(2); sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; bsub, Bacillus subtilis; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

Peptidase_M4_C1Thermolysin metallopeptidase, alpha-helical domain379-553190.51.9e-56

Peptidase_M41Thermolysin metallopeptidase, catalytic domain225-375168.01.7e-49

FTP1Fungalysin/Thermolysin Propeptide Motif85-13159.12.5e-16

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_202497975.1 M4 family metallopeptidase [Streptomyces sp. SID5469] 25060.0e+00
WP_190173207.1 M4 family metallopeptidase [Streptomyces mirabilis] >dbj 22960.0e+00
QIY98356.1 peptidase M4 [Streptomyces sp. S1D4-11] 22930.0e+00
WP_168495699.1 MULTISPECIES: M4 family metallopeptidase [Streptomyces] >gb 22930.0e+00
WP_095852522.1 MULTISPECIES: M4 family metallopeptidase [unclassified Strep... 22850.0e+00
WP_075032964.1 M4 family metallopeptidase [Streptomyces mirabilis] >emb 22810.0e+00
WP_217568343.1 M4 family metallopeptidase [Streptomyces sp. GbtcB7] 22800.0e+00
WP_067370699.1 M4 family metallopeptidase [Streptomyces olivochromogenes] >... 22710.0e+00
WP_143602961.1 MULTISPECIES: M4 family metallopeptidase [unclassified Strep... 22690.0e+00
WP_143614692.1 MULTISPECIES: M4 family metallopeptidase [unclassified Strep... 22690.0e+00

PSORT result

LocalizationCertaintyPSORT said
outside0.3000 Seems to have a cleavable N-term signal seq.