-- | --

IDSAVERM_2895 TypeCDS
From3567272 nt length10842
To3556431 aa length3613
GeneolmA7 pI4.66
Definitionmodular polyketide synthase M.W (Da)379243
Noteoligomycin gene cluster AseI frg.K
SignalP v.4.0Non-secretory protein | plot Categoryantibiotic production


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
sgrSGR_6073 putative type-I PKS28680.0e+00
samSAM23877_7114 modular polyketide synthase (KS-AT-DH-ER-KR-ACP-KS-AT-KR-ACP-KS-AT-DH-KR-ACP)26060.0e+00

*sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

ketoacyl-synt2Beta-ketoacyl synthase, N-terminal domain33-282, 1565-1812565.51.2e-170

Acyl_transf_12Acyl transferase domain573-891, 2091-2401494.81.1e-148

KR2KR domain1191-1368, 2940-3118381.74.6e-115

Ketoacyl-synt_C2Beta-ketoacyl synthase, C-terminal domain290-407, 1820-1937287.08.5e-87

PS-DH1Polyketide synthase dehydratase2451-2725176.37.6e-52

KAsynt_C_assoc2Ketoacyl-synthetase C-terminal extension410-532, 1940-2053120.44.4e-35

PP-binding2Phosphopantetheine attachment site1478-1543, 3227-3292100.93.4e-29

adh_short2short chain dehydrogenase1192-1349, 2941-310094.36e-27

adh_short_C21Enoyl-(Acyl carrier protein) reductase1200-134860.31.8e-16

Epimerase2NAD dependent epimerase/dehydratase family1193-1331, 2942-307759.13.9e-16

Thiolase_N2Thiolase, N-terminal domain187-241, 1703-176552.05.8e-14

Thioesterase1Thioesterase domain3416-359650.92e-13

GDP_Man_Dehyd1GDP-mannose 4,6 dehydratase1194-129438.48.2e-10

Docking1Erythronolide synthase docking2-2637.99.1e-10

Polysacc_synt_21Polysaccharide biosynthesis protein1193-133135.64.9e-09

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_189974492.1 type I polyketide synthase [Streptomyces avidinii] >lcl 131670.0e+00
WP_109781644.1 type I polyketide synthase [Streptomyces sp. CG 926] >gb 130910.0e+00
WP_079160169.1 type I polyketide synthase [Streptomyces pactum] >gb 128160.0e+00
AAS46345.1 NlmA7 [Streptomyces nanchangensis] 127890.0e+00
WP_229920904.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces avi... 95440.0e+00
WP_055526186.1 type I polyketide synthase [Streptomyces graminilatus] 86310.0e+00
WP_164396245.1 SDR family NAD(P)-dependent oxidoreductase, partial [Strepto... 82600.0e+00
WP_187745072.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces ros... 81790.0e+00
WP_220238838.1 SDR family NAD(P)-dependent oxidoreductase [Amycolatopsis sp... 81570.0e+00
WP_184908670.1 type I polyketide synthase [Streptomyces luteogriseus] >lcl 76920.0e+00

PSORT result

LocalizationCertaintyPSORT said
membrane0.2168 Seems to have no N-terminal signal seq.