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IDSAVERM_2896 TypeCDS
From3581388 nt length14058
To3567331 aa length4685
GeneolmA6 pI4.48
Definitionmodular polyketide synthase M.W (Da)489366
Noteoligomycin gene cluster AseI frg.K
SignalP v.4.0Non-secretory protein | plot Categoryantibiotic production


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
scabSCAB83921 putative modular polyketide synthase38680.0e+00
saceSACE_0724 EryAIII Erythromycin polyketide synthase modules 5 and 624640.0e+00
cglugi|19554061 COG3321:Polyketide synthase modules and related proteins [Corynebacterium glutamicum]5599.7e-160

*scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; cglu, Corynebacterium glutamicum;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

Acyl_transf_13Acyl transferase domain568-886, 2096-2414, 3616-3934906.08e-274

ketoacyl-synt3Beta-ketoacyl synthase, N-terminal domain35-275, 1567-1807, 3089-3328805.37.9e-244

KR3KR domain1187-1366, 2714-2889, 4242-4421479.54.4e-145

Ketoacyl-synt_C3Beta-ketoacyl synthase, C-terminal domain283-400, 1815-1932, 3336-3453435.86.1e-133

KAsynt_C_assoc3Ketoacyl-synthetase C-terminal extension403-530, 1935-2061, 3456-3580175.24.4e-52

adh_short3short chain dehydrogenase1188-1304, 2715-2872, 4243-4349151.51.7e-44

PP-binding3Phosphopantetheine attachment site1477-1542, 3000-3065, 4534-4599146.12.7e-43

Epimerase3NAD dependent epimerase/dehydratase family1189-1330, 2716-2849, 4244-4385117.17.6e-34

GDP_Man_Dehyd2GDP-mannose 4,6 dehydratase1190-1330, 2717-2801102.13.6e-29

Polysacc_synt_23Polysaccharide biosynthesis protein1189-1328, 2716-2799, 4244-438384.46.9e-24

Thiolase_N1Thiolase, N-terminal domain1708-176075.05.5e-21

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_209468378.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces avi... 163120.0e+00
WP_184908671.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces lut... 159820.0e+00
AQS67523.1 hypothetical protein B1H29_11765 [Streptomyces pactum] 154060.0e+00
WP_208638333.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces pac... 153950.0e+00
AAS46344.1 NlmA6 [Streptomyces nanchangensis] 153700.0e+00
WP_044383942.1 type I polyketide synthase [Streptomyces cyaneogriseus] >gb 148560.0e+00
WP_234392997.1 SDR family NAD(P)-dependent oxidoreductase, partial [Strepto... 116400.0e+00
PWK61276.1 acyl transferase domain-containing protein, partial [Streptomyces... 99670.0e+00
APD71586.1 type I polyketide synthase 3 [Streptomyces sp.] 99110.0e+00
WP_192939082.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces cin... 98580.0e+00

PSORT result

LocalizationCertaintyPSORT said
membrane0.3060 Seems to have no N-terminal signal seq.