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IDSAVERM_2897 TypeCDS
From3593353 nt length11820
To3581534 aa length3939
GeneolmA3 pI4.81
Definitionmodular polyketide synthase M.W (Da)410491
Noteoligomycin gene cluster AseI frg.K
SignalP v.4.0Non-secretory protein | plot Categoryantibiotic production


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
sgrSGR_6371 putative type-I PKS26060.0e+00
saceSACE_4139 type I modular polyketide synthase31760.0e+00
nfarnfa43240 polyketide synthase8370.0e+00
mtubgi|15609185 Probable polyketide synthase pks12 [Mycobacterium tuberculosis H37Rv]31800.0e+00

*sgr, Streptomyces griseus IFO13350; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

ketoacyl-synt2Beta-ketoacyl synthase, N-terminal domain34-284, 2113-2356565.99e-171

Acyl_transf_12Acyl transferase domain572-891, 2636-2955480.62.4e-144

PS-DH2Polyketide synthase dehydratase939-1214, 3004-3279384.04.3e-115

KR2KR domain1734-1912, 3505-3683370.11.7e-111

Ketoacyl-synt_C2Beta-ketoacyl synthase, C-terminal domain292-409, 2364-2481284.74.3e-86

KAsynt_C_assoc2Ketoacyl-synthetase C-terminal extension412-536, 2484-2597127.33.3e-37

PP-binding2Phosphopantetheine attachment site2020-2086, 3790-385693.85.4e-27

adh_short2short chain dehydrogenase1735-1892, 3507-366676.81.3e-21

ADH_zinc_N1Zinc-binding dehydrogenase1556-164763.31.9e-17

Thiolase_N2Thiolase, N-terminal domain196-243, 2260-231059.13.8e-16

ADH_zinc_N_21Zinc-binding dehydrogenase1589-172358.31.6e-15

adh_short_C21Enoyl-(Acyl carrier protein) reductase3516-366550.81.4e-13

Epimerase2NAD dependent epimerase/dehydratase family1736-1870, 3508-369950.02.4e-13

Docking1Erythronolide synthase docking2-2746.91.4e-12

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_217215489.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces sp.... 140380.0e+00
WP_184908672.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces lut... 139600.0e+00
WP_095754038.1 type I polyketide synthase [Streptomyces sp. SA15] >gb 138910.0e+00
WP_030855002.1 type I polyketide synthase [Streptomyces sp. NRRL S-475] 138660.0e+00
WP_055417835.1 type I polyketide synthase [Streptomyces pactum] >gb 137130.0e+00
WP_189973980.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces avi... 132860.0e+00
WP_109783604.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces sp.... 132420.0e+00
AAS46343.1 NlmA3 [Streptomyces nanchangensis] 123830.0e+00
WP_164395364.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces har... 105290.0e+00
WP_044383940.1 type I polyketide synthase [Streptomyces cyaneogriseus] >gb 105140.0e+00

PSORT result

LocalizationCertaintyPSORT said
membrane0.2062 Seems to have no N-terminal signal seq.