| ID | SAVERM_3314
| Type | CDS
|
| From | 4126277
| nt length | 1044
|
| To | 4125234
| aa length | 347
|
| Gene | adhA4
| pI | 4.57
|
| Definition | putative NADP-dependent alcohol dehydrogenase
| M.W (Da) | 36700
|
| Note | PF00107: Zinc-binding dehydrogenase
| AseI frg. | E
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | specific pathways
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO4945 putative dehydrogenase | 582 | 0.0e+00
|
| sgr | SGR_6892 putative dehydrogenase | 571 | 0.0e+00
|
| sam | SAM23877_4767 putative oxidoreductase, Zn-dependent and NAD(P)-binding | 575 | 0.0e+00
|
| scab | SCAB34421 putative NADP-dependent alcohol dehydrogenase | 607 | 0.0e+00
|
| sace | SACE_1843 NADP-dependent alcohol dehydrogenase | 529 | 0.0e+00
|
| nfar | nfa52260 dehydrogenase | 447 | 6.3e-127
|
| mtub | gi|15610182 PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC [Mycobacterium tuberculosis H37Rv] | 465 | 2.2e-132
|
| cglu | gi|19551580 COG1064:Zn-dependent alcohol dehydrogenases [Corynebacterium glutamicum] | 389 | 1.1e-109
|
| bsub | BG12562 adhA; NADP-dependent alcohol dehydrogenase [EC:1.1.1.2] | 471 | 2.1e-134
|
| ecoli | gi|16128310 putative dehydrogenase, NAD(P)-binding [Escherichia coli K12] | 349 | 1.8e-97
|
| paer | PA2275 [gene=PA2275] [prot=probable alcohol dehydrogenase (Zn-dependent)] [comment=PA2275] | 376 | 1.9e-105
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| ADH_N | 1 | Alcohol dehydrogenase GroES-like domain | 31-144 | 98.8 | 1.5e-28
|
| ADH_zinc_N | 1 | Zinc-binding dehydrogenase | 186-308 | 74.2 | 8.2e-21
|
| AlaDh_PNT_C | 1 | Alanine dehydrogenase/PNT, C-terminal domain | 178-249 | 26.1 | 4.3e-06
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_153288916.1 | NAD(P)-dependent alcohol dehydrogenase [Streptomyces fagopyr...
| 1599 | 0.0e+00 |
| WP_148010189.1 | NAD(P)-dependent alcohol dehydrogenase [Streptomyces sp. me1...
| 1588 | 0.0e+00 |
| WP_234513204.1 | NAD(P)-dependent alcohol dehydrogenase [Streptomyces glomera...
| 1573 | 0.0e+00 |
| WP_099499561.1 | MULTISPECIES: NAD(P)-dependent alcohol dehydrogenase [Strept...
| 1573 | 0.0e+00 |
| WP_055493357.1 | NAD(P)-dependent alcohol dehydrogenase [Streptomyces sp. TP-...
| 1572 | 0.0e+00 |
| WP_168529931.1 | NAD(P)-dependent alcohol dehydrogenase [Streptomyces sp. RPA...
| 1564 | 0.0e+00 |
| PJN06621.1 | alcohol dehydrogenase [Streptomyces sp. CB01635]
| 1561 | 0.0e+00 |
| WP_199842067.1 | NAD(P)-dependent alcohol dehydrogenase [Streptomyces sp. CB0...
| 1561 | 0.0e+00 |
| WP_206302081.1 | NAD(P)-dependent alcohol dehydrogenase [Streptomyces sp. AcE...
| 1561 | 0.0e+00 |
| WP_181650210.1 | NAD(P)-dependent alcohol dehydrogenase [Streptomyces sp. WAC...
| 1560 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.1095 | Seems to have no N-terminal signal seq.
|