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IDSAVERM_3444 TypeCDS
From4269417 nt length1584
To4267834 aa length527
GenepurH pI5.19
Definitionputative bifunctional purine biosynthesis protein M.W (Da)55867
NotePF01808: AICARFT/IMPCHase bienzyme AseI frg.E
SignalP v.4.0Non-secretory protein | plot Categorymetabolism of nucleotides & nucleic acids

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO4814 purH bifunctional purine biosynthesis protein9310.0e+00
sgrSGR_2717 putative bifunctional purine biosynthesis protein9110.0e+00
samSAM23877_4630 Bifunctional purine biosynthesis protein PurH9470.0e+00
scabSCAB35741 putative bifunctional purine biosynthesis protein9410.0e+00
saceSACE_6664 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase7210.0e+00
nfarnfa49860 purHJ phosphoribosylaminoimidazole carboxy formyl formyltransferase/inosine-monophosphate cyclohydrolase7260.0e+00
mtubgi|15608097 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Mycobacterium tuberculosis H37Rv]7020.0e+00
cglugi|19552088 COG0138:AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [Corynebacterium glutamicum]7040.0e+00
bsubBG10710 purH, purJ, purHJ; phosphoribosylaminoimidazole carboxy formyl formyltransferase / inosine-monophosphate cyclohydrolase [EC:2.1.2.3 3.5.4.10]4501.1e-127
ecoligi|16131836 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Escherichia coli K12]4276.4e-121
paerPA4854 [gene=purH] [prot=phosphoribosylaminoimidazolecarboxamide formyltransferase] [comment=PA4854]4216.4e-119

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

AICARFT_IMPCHas1AICARFT/IMPCHase bienzyme147-460380.45.8e-114

MGS1MGS-like domain29-14185.02.7e-24

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_067017954.1 bifunctional phosphoribosylaminoimidazolecarboxamide formylt... 23070.0e+00
NUT30710.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransf... 23010.0e+00
WP_119100597.1 bifunctional phosphoribosylaminoimidazolecarboxamide formylt... 23000.0e+00
WP_235475398.1 bifunctional phosphoribosylaminoimidazolecarboxamide formylt... 22980.0e+00
WP_128433238.1 bifunctional phosphoribosylaminoimidazolecarboxamide formylt... 22950.0e+00
WP_046727308.1 bifunctional phosphoribosylaminoimidazolecarboxamide formylt... 22930.0e+00
WP_115507671.1 bifunctional phosphoribosylaminoimidazolecarboxamide formylt... 22930.0e+00
WP_055493259.1 bifunctional phosphoribosylaminoimidazolecarboxamide formylt... 22910.0e+00
WP_071367129.1 bifunctional phosphoribosylaminoimidazolecarboxamide formylt... 22910.0e+00
WP_055625280.1 bifunctional phosphoribosylaminoimidazolecarboxamide formylt... 22900.0e+00

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.1746 Seems to have no N-terminal signal seq.