| ID | SAVERM_3479
| Type | CDS
|
| From | 4312144
| nt length | 1578
|
| To | 4310567
| aa length | 525
|
| Gene | guaA
| pI | 4.51
|
| Definition | putative GMP synthase
| M.W (Da) | 56785
|
| Note | PF00117: Glutamine amidotransferase class-I
| AseI frg. | E
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of nucleotides & nucleic acids
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO4785 guaA GMP synthase | 960 | 0.0e+00
|
| sgr | SGR_2745 putative GMP synthase | 978 | 0.0e+00
|
| sam | SAM23877_4599 GMP synthetase (glutamine aminotransferase) | 964 | 0.0e+00
|
| scab | SCAB36051 putative GMP synthase | 1004 | 0.0e+00
|
| sace | SACE_6701 GMP synthase glutamine amidotransferase | 793 | 0.0e+00
|
| nfar | nfa8970 guaA GMP synthase | 767 | 0.0e+00
|
| mtub | gi|15610532 bifunctional GMP synthase/glutamine amidotransferase protein [Mycobacterium tuberculosis H37Rv] | 732 | 0.0e+00
|
| cglu | gi|19551841 COG0518:GMP synthase - Glutamine amidotransferase domain [Corynebacterium glutamicum] | 741 | 0.0e+00
|
| bsub | BG10647 guaA, guaB; GMP synthase [EC:6.3.5.2] | 554 | 4.0e-159
|
| ecoli | gi|16130432 bifunctional GMP synthase/glutamine amidotransferase protein [Escherichia coli K12] | 498 | 5.0e-142
|
| paer | PA3769 [gene=guaA] [prot=GMP synthase] [comment=PA3769] | 503 | 1.3e-143
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| GATase | 1 | Glutamine amidotransferase class-I | 15-195 | 142.9 | 8.8e-42
|
| GMP_synt_C | 1 | GMP synthase C terminal domain | 432-524 | 130.8 | 1.3e-38
|
| Peptidase_C26 | 1 | Peptidase C26 | 74-179 | 43.1 | 3.7e-11
|
| NAD_synthase | 1 | NAD synthase | 217-291 | 41.9 | 5.5e-11
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_202498091.1 | glutamine-hydrolyzing GMP synthase [Streptomyces sp. SID5469...
| 2688 | 0.0e+00 |
| WP_151477077.1 | glutamine-hydrolyzing GMP synthase [Streptomyces albicerus]
| 2676 | 0.0e+00 |
| WP_189837192.1 | glutamine-hydrolyzing GMP synthase [Streptomyces umbrinus] >...
| 2669 | 0.0e+00 |
| WP_037626819.1 | glutamine-hydrolyzing GMP synthase [Streptomyces aureus]
| 2667 | 0.0e+00 |
| WP_103552750.1 | glutamine-hydrolyzing GMP synthase [Streptomyces populi] >gb...
| 2666 | 0.0e+00 |
| WP_151469167.1 | glutamine-hydrolyzing GMP synthase [Streptomyces triticiradi...
| 2666 | 0.0e+00 |
| WP_200396330.1 | glutamine-hydrolyzing GMP synthase [Streptomyces sp. ZYC-3] ...
| 2665 | 0.0e+00 |
| WP_190229536.1 | glutamine-hydrolyzing GMP synthase [Streptomyces umbrinus] >...
| 2664 | 0.0e+00 |
| WP_086804725.1 | glutamine-hydrolyzing GMP synthase [Streptomyces caniscabiei...
| 2652 | 0.0e+00 |
| WP_184904513.1 | MULTISPECIES: glutamine-hydrolyzing GMP synthase [unclassifi...
| 2652 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| membrane | 0.1256 | Seems to have no N-terminal signal seq.
|