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IDSAVERM_3968 TypeCDS
From4895001 nt length525
To4894477 aa length174
GeneispF pI5.19
Definitionputative 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase M.W (Da)17499
NoteMEP pathway, EC 4.6.1.12 AseI frg.G1
SignalP v.4.0Non-secretory protein | plot Categoryspecific pathways


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO4234 putative 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase2835.0e-100
sgrSGR_4013 "putative 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase"2751.0e-96
samSAM23877_3466 2-C-methyl-D-erythritol 2, 4-cyclodiphosphate synthase2916.0e-103
scabSCAB50101 putative 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase2893.0e-102
saceSACE_0440 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase1901.0e-63
nfarnfa4370 mecs 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase1912.3e-50
mtubgi|15610717 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Mycobacterium tuberculosis H37Rv]1705.6e-44
cglugi|19553856 COG0245:2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Corynebacterium glutamicum]1681.2e-43
bsubBG10153 ispF, yacN; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase1029.7e-24
ecoligi|16130653 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Escherichia coli K12]1012.4e-23
paerPA3627 [gene=PA3627] [prot=conserved hypothetical protein] [comment=PA3627]991.2e-22

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

YgbB1YgbB family21-170150.25.2e-44

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_130441911.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Strep... 7582.6e-101
WP_095752262.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Strep... 7574.4e-101
WP_124441137.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Strep... 7567.3e-101
WP_145875949.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Strep... 7532.1e-100
WP_136100689.1 MULTISPECIES: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate s... 7513.1e-100
WP_199378359.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Strep... 7513.4e-100
WP_153543383.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Strep... 7513.6e-100
WP_093475880.1 MULTISPECIES: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate s... 7503.6e-100
WP_128790649.1 MULTISPECIES: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate s... 7503.7e-100
WP_181797917.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Strep... 7503.9e-100

PSORT result

LocalizationCertaintyPSORT said
Not Clear Seems to have an uncleavable N-term signal seq