| ID | SAVERM_4119
| Type | CDS
|
| From | 5053286
| nt length | 1131
|
| To | 5052156
| aa length | 376
|
| Gene | ribD
| pI | 5.68
|
| Definition | putative diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal)/ 5-amino-6-(5-phosphoribosylamino) uracil reductase
| M.W (Da) | 39881
|
| Note | PF01872: RibD C-terminal domain
| AseI frg. | H
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of coenzymes & prosthetic groups
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO4106 putative bifunctional enzyme deaminase/reductase | 558 | 0.0e+00
|
| sam | SAM23877_3579 5-amino-6-(5-phosphoribosylamino)uracil reductase | 547 | 0.0e+00
|
| scab | SCAB48981 putative diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal)/ 5-amino-6-(5-phosphoribosylamino) uracil reductase | 569 | 0.0e+00
|
| sace | SACE_2887 riboflavin-specific deaminase | 70 | 4.0e-14
|
| nfar | nfa780 reductase/deaminase | 376 | 2.0e-105
|
| cglu | gi|19552809 COG0117:Pyrimidine deaminase [Corynebacterium glutamicum] | 59 | 2.2e-10
|
| bsub | BG10518 ribG; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] | 65 | 5.0e-12
|
| ecoli | gi|16128399 bifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); 5-amino-6-(5-phosphoribosylamino) uracil reductase [Escherichia coli K12] | 55 | 4.5e-09
|
| paer | PA4056 [gene=ribD] [prot=riboflavin-specific deaminase/reductase] [comment=PA4056] | 65 | 7.7e-12
|
*coel, Streptomyces coelicolor A3(2); sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| RibD_C | 1 | RibD C-terminal domain | 4-213 | 140.6 | 5e-41
|
| dCMP_cyt_deam_1 | 1 | Cytidine and deoxycytidylate deaminase zinc-binding region | 231-332 | 58.9 | 3.4e-16
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_152781917.1 | dihydrofolate reductase family protein [Streptomyces phyllan...
| 1581 | 0.0e+00 |
| WP_059130143.1 | dihydrofolate reductase family protein [Streptomyces sp. NRR...
| 1556 | 0.0e+00 |
| WP_152865792.1 | dihydrofolate reductase family protein [Streptomyces acidico...
| 1556 | 0.0e+00 |
| WP_189219159.1 | dihydrofolate reductase family protein [Streptomyces ruber] ...
| 1555 | 0.0e+00 |
| WP_220293541.1 | dihydrofolate reductase family protein [Streptomyces sp. MBT...
| 1552 | 0.0e+00 |
| WP_161238209.1 | dihydrofolate reductase family protein [Streptomyces sp. SID...
| 1550 | 0.0e+00 |
| WP_153289782.1 | dihydrofolate reductase family protein [Streptomyces fagopyr...
| 1546 | 0.0e+00 |
| WP_043441695.1 | dihydrofolate reductase family protein [Streptomyces nodosus...
| 1542 | 0.0e+00 |
| WP_131570863.1 | dihydrofolate reductase family protein [Streptomyces sp. KM2...
| 1541 | 0.0e+00 |
| WP_148009145.1 | dihydrofolate reductase family protein [Streptomyces sp. me1...
| 1537 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| Not Clear | | Seems to have an uncleavable N-term signal seq
|