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IDSAVERM_415 TypeCDS
From508904 nt length10059
To498846 aa length3352
GenepteA5 pI5.12
Definitionmodular polyketide synthase M.W (Da)353401
Notefilipin gene cluster AseI frg.A
SignalP v.4.0Non-secretory protein | plot Categoryantibiotic production


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

ketoacyl-synt2Beta-ketoacyl synthase, N-terminal domain35-285, 1527-1777619.25e-187

Acyl_transf_12Acyl transferase domain563-860, 2068-2386451.71.6e-135

KR2KR domain1157-1331, 2697-2874373.02.1e-112

Ketoacyl-synt_C2Beta-ketoacyl synthase, C-terminal domain293-410, 1785-1902299.98.4e-91

KAsynt_C_assoc2Ketoacyl-synthetase C-terminal extension413-528, 1905-2032102.81.3e-29

PP-binding2Phosphopantetheine attachment site1438-1504, 2990-304997.34.5e-28

adh_short2short chain dehydrogenase1158-1315, 2698-285586.51.5e-24

Epimerase2NAD dependent epimerase/dehydratase family1159-1294, 2699-282465.45e-18

Thiolase_N2Thiolase, N-terminal domain190-241, 1686-173354.31.1e-14

Thioesterase1Thioesterase domain3133-322853.92.5e-14

GDP_Man_Dehyd1GDP-mannose 4,6 dehydratase1160-124450.71.5e-13

Docking1Erythronolide synthase docking3-2839.33.3e-10

Polysacc_synt_21Polysaccharide biosynthesis protein1159-128639.43.5e-10

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_069925208.1 type I polyketide synthase [Streptomyces agglomeratus] >gb 139630.0e+00
WP_069933655.1 type I polyketide synthase [Streptomyces agglomeratus] >gb 139510.0e+00
WP_070343544.1 type I polyketide synthase [Streptomyces agglomeratus] >gb 139360.0e+00
GGV03241.1 hypothetical protein GCM10010260_44880 [Streptomyces filipinensi... 137340.0e+00
AOR30416.1 polyketide synthase [Streptomyces fodineus] 136210.0e+00
GGX74571.1 hypothetical protein GCM10010324_19900 [Streptomyces hiroshimens... 133300.0e+00
WP_179084382.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces rec... 133160.0e+00
133070.0e+00
PSJ26256.1 polyketide synthase [Streptosporangium nondiastaticum] 132580.0e+00
WP_058047815.1 type I polyketide synthase [Streptomyces roseifaciens] 132180.0e+00

PSORT result

LocalizationCertaintyPSORT said
membrane0.1447 Seems to have no N-terminal signal seq.