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IDSAVERM_416 TypeCDS
From527388 nt length18438
To508951 aa length6145
GenepteA4 pI4.75
Definitionmodular polyketide synthase M.W (Da)642037
Notefilipin gene cluster AseI frg.A
SignalP v.4.0Non-secretory protein | plot Categoryantibiotic production


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
samSAM23877_7119 modular polyketide synthase (KS-AT-KR-ACP-KS-AT-KR-ACP-KS-AT-KR-ACP-KS-AT-KR-ACP-TE)48780.0e+00

*sam, Streptomyces ambofaciens ATCC 23877;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

ketoacyl-synt4Beta-ketoacyl synthase, N-terminal domain19-269, 1543-1793, 3045-3295, 4576-48261214.20

KR4KR domain1171-1345, 2675-2849, 4202-4375, 5711-5884736.94.4e-224

Acyl_transf_14Acyl transferase domain559-860, 2072-2370, 3576-3857, 5103-5400726.92.6e-219

Ketoacyl-synt_C4Beta-ketoacyl synthase, C-terminal domain277-394, 1801-1918, 3303-3420, 4834-4951586.71e-179

KAsynt_C_assoc4Ketoacyl-synthetase C-terminal extension397-488, 1921-2017, 3423-3541, 4954-5069196.61e-58

PP-binding4Phosphopantetheine attachment site1455-1521, 2956-3022, 4486-4551, 5992-6058175.02.5e-52

adh_short4short chain dehydrogenase1172-1327, 2676-2830, 4203-4359, 5712-5867165.87.2e-49

Epimerase4NAD dependent epimerase/dehydratase family1173-1303, 2677-2806, 4204-4341, 5713-5847140.55.5e-41

GDP_Man_Dehyd1GDP-mannose 4,6 dehydratase5714-5847104.95.1e-30

Thiolase_N4Thiolase, N-terminal domain174-226, 1695-1746, 3184-3248, 4733-4781103.41.2e-29

Polysacc_synt_24Polysaccharide biosynthesis protein1173-1273, 2677-2804, 4204-4296, 5713-5840101.83.4e-29

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_042492670.1 MULTISPECIES: type I polyketide synthase [Streptomyces] >gb 274620.0e+00
WP_070343543.1 type I polyketide synthase [Streptomyces agglomeratus] >gb 251940.0e+00
WP_069933654.1 type I polyketide synthase [Streptomyces agglomeratus] >gb 251930.0e+00
WP_069777069.1 type I polyketide synthase [Streptomyces fodineus] >gb 247070.0e+00
WP_235483078.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces ros... 243020.0e+00
WP_179084381.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces rec... 239980.0e+00
WP_229899094.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces hir... 239000.0e+00
GGX74581.1 hypothetical protein GCM10010324_19910 [Streptomyces hiroshimens... 238950.0e+00
WP_194961213.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces sp.... 238910.0e+00
WP_120752864.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces kle... 238250.0e+00

PSORT result

LocalizationCertaintyPSORT said
membrane0.3272 Seems to have no N-terminal signal seq.