| ID | SAVERM_4305
| Type | CDS
|
| From | 5277067
| nt length | 972
|
| To | 5278038
| aa length | 323
|
| Gene | trxB1
| pI | 4.61
|
| Definition | putative thioredoxin reductase (NADPH)
| M.W (Da) | 34185
|
| Note | PF00070: Pyridine nucleotide-disulphide oxidoreductase
| AseI frg. | H
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | membrane bioenergetics
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO3890 thioredoxin reductase (NADPH) | 617 | 0.0e+00
|
| sgr | SGR_3689 putative thioredoxin reductase (NADPH) | 601 | 0.0e+00
|
| sam | SAM23877_3767 Thioredoxin reductase | 613 | 0.0e+00
|
| scab | SCAB45931 putative thioredoxin reductase (NADPH) | 583 | 0.0e+00
|
| sace | SACE_7384 thioredoxin reductase | 400 | 2.0e-141
|
| nfar | nfa56620 thioredoxin reductase | 391 | 3.7e-110
|
| mtub | gi|15611049 PROBABLE THIOREDOXIN REDUCTASE TRXB2 (TRXR) (TR) [Mycobacterium tuberculosis H37Rv] | 368 | 3.4e-103
|
| cglu | gi|19554280 COG0492:Thioredoxin reductase [Corynebacterium glutamicum] | 353 | 6.1e-99
|
| bsub | BG12398 trxB, yvcH; thioredoxin reductase (general stress protein 35) [EC:1.6.4.5] | 251 | 5.3e-68
|
| ecoli | gi|16128855 thioredoxin reductase [Escherichia coli K12] | 272 | 1.9e-74
|
| paer | PA0849 [gene=trxB2] [prot=thioredoxin reductase 2] [comment=PA0849] | 291 | 4.2e-80
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| Pyr_redox_2 | 1 | Pyridine nucleotide-disulphide oxidoreductase | 6-295 | 160.1 | 6.2e-47
|
| Pyr_redox | 1 | Pyridine nucleotide-disulphide oxidoreductase | 149-219 | 67.0 | 1.5e-18
|
| Pyr_redox_3 | 1 | Pyridine nucleotide-disulphide oxidoreductase | 83-278 | 62.0 | 4.9e-17
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_202498239.1 | thioredoxin-disulfide reductase [Streptomyces sp. SID5469]
| 1619 | 0.0e+00 |
| OSZ59786.1 | thioredoxin-disulfide reductase [Streptomyces pharetrae CZA14]
| 1572 | 0.0e+00 |
| WP_189862711.1 | thioredoxin-disulfide reductase [Streptomyces poonensis] >db...
| 1571 | 0.0e+00 |
| WP_071366676.1 | thioredoxin-disulfide reductase [Streptomyces colonosanans] ...
| 1570 | 0.0e+00 |
| WP_030376941.1 | MULTISPECIES: thioredoxin-disulfide reductase [unclassified ...
| 1570 | 0.0e+00 |
| WP_086738276.1 | thioredoxin-disulfide reductase [Streptomyces glaucescens]
| 1568 | 0.0e+00 |
| WP_028804101.1 | thioredoxin-disulfide reductase [Streptomyces sp. 142MFCol3....
| 1567 | 0.0e+00 |
| WP_200421641.1 | thioredoxin-disulfide reductase [Streptomyces sp. Y2F8-2] >d...
| 1566 | 0.0e+00 |
| WP_095935438.1 | thioredoxin-disulfide reductase [Streptomyces sp. Tue6028] >...
| 1566 | 0.0e+00 |
| WP_006141305.1 | MULTISPECIES: thioredoxin-disulfide reductase [Streptomyces]...
| 1566 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| Not Clear | | Seems to have an uncleavable N-term signal seq
|