| ID | SAVERM_4522
| Type | CDS
|
| From | 5524875
| nt length | 549
|
| To | 5525423
| aa length | 182
|
| Gene | pyrE
| pI | 4.9
|
| Definition | putative orotate phosphoribosyltransferase
| M.W (Da) | 19033
|
| Note | PF00156: Phosphoribosyl transferase domain
| AseI frg. | L
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of nucleotides & nucleic acids
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO3650 putative uridine 5'-monophosphate synthase | 306 | 6.0e-109
|
| sgr | SGR_3419 putative orotate phosphoribosyltransferase | 245 | 1.0e-84
|
| sam | SAM23877_3968 Orotate phosphoribosyltransferase | 317 | 3.0e-113
|
| scab | SCAB42171 putative orotate phosphoribosyltransferase | 309 | 7.0e-110
|
| sace | SACE_7189 orotate phosphoribosyltransferase | 201 | 3.0e-67
|
| nfar | nfa53980 pyrE orotate phosphoribosyltransferase | 221 | 2.9e-59
|
| mtub | gi|57116728 orotate phosphoribosyltransferase [Mycobacterium tuberculosis H37Rv] | 211 | 2.4e-56
|
| cglu | gi|19553965 COG0461:Orotate phosphoribosyltransferase [Corynebacterium glutamicum] | 217 | 2.3e-58
|
| bsub | BG10720 pyrE, pyrX; orotate phosphoribosyltransferase [EC:2.4.2.10] | 66 | 8.2e-13
|
| ecoli | gi|16131513 orotate phosphoribosyltransferase [Escherichia coli K12] | 46 | 1.0e-06
|
| paer | PA5331 [gene=pyrE] [prot=orotate phosphoribosyltransferase] [comment=PA5331] | 48 | 3.5e-07
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| Pribosyltran | 1 | Phosphoribosyl transferase domain | 58-161 | 46.0 | 3.6e-12
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_069779633.1 | orotate phosphoribosyltransferase [Streptomyces fodineus] >g...
| 603 | 2.4e-77 |
| WP_189957384.1 | orotate phosphoribosyltransferase [Streptomyces alanosinicus...
| 599 | 8.7e-77 |
| WP_031172616.1 | MULTISPECIES: orotate phosphoribosyltransferase [Streptomyce...
| 598 | 1.5e-76 |
| WP_189188742.1 | orotate phosphoribosyltransferase [Streptomyces albiflavesce...
| 598 | 1.5e-76 |
| WP_043371624.1 | MULTISPECIES: orotate phosphoribosyltransferase [Streptomyce...
| 597 | 1.8e-76 |
| WP_208899688.1 | orotate phosphoribosyltransferase [Streptomyces incarnatus] ...
| 597 | 2.0e-76 |
| WP_039650530.1 | MULTISPECIES: orotate phosphoribosyltransferase [Streptomyce...
| 596 | 2.4e-76 |
| WP_129307802.1 | orotate phosphoribosyltransferase [Streptomyces sp. L2]
| 596 | 2.8e-76 |
| WP_093723129.1 | orotate phosphoribosyltransferase [Streptomyces sp. DI166] >...
| 596 | 2.9e-76 |
| WP_150951682.1 | orotate phosphoribosyltransferase [Streptomyces luteolifulvu...
| 595 | 3.5e-76 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.2680 | Seems to have no N-terminal signal seq.
|