| ID | SAVERM_4583
| Type | CDS
|
| From | 5599337
| nt length | 2292
|
| To | 5597046
| aa length | 763
|
| Gene | pbp8
| pI | 9.41
|
| Definition | putative penicillin-binding protein, secreted
| M.W (Da) | 80134
|
| Note | PF00912: Transglycosylase
| AseI frg. | L
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | cell wall
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO3580 putative transpeptidase | 1048 | 0.0e+00
|
| sgr | SGR_3341 putative penicillin-binding protein | 870 | 0.0e+00
|
| sam | SAM23877_4081 putative Penicillin-binding protein 2D | 1136 | 0.0e+00
|
| scab | SCAB41401 putative penicillin-binding protein, secreted | 1145 | 0.0e+00
|
| sace | SACE_0314 penicillin binding protein (class A) | 355 | 3.0e-111
|
| nfar | nfa3390 penicillin-binding protein | 317 | 1.9e-87
|
| mtub | gi|57117145 PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE (PEPTIDOGLYCAN TGASE) + PENICILLIN-SENSITIVE TRANSPEPTIDASE (DD-TRANSPEPTIDASE)] [Mycobacterium tuberculosis H37Rv] | 285 | 1.0e-77
|
| cglu | gi|19551529 COG0744:Membrane carboxypeptidase (penicillin-binding protein) [Corynebacterium glutamicum] | 319 | 2.6e-88
|
| bsub | BG12459 ywhE; penicillin-binding protein | 243 | 3.0e-65
|
| paer | PA4700 [gene=mrcB] [prot=penicillin-binding protein 1B] [comment=PA4700] | 207 | 2.9e-54
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| Transgly | 1 | Transglycosylase | 78-261 | 213.9 | 1e-63
|
| Transpeptidase | 1 | Penicillin binding protein transpeptidase domain | 362-637 | 98.7 | 3.3e-28
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_209508419.1 | penicillin-binding protein [Streptomyces griseochromogenes] ...
| 3032 | 0.0e+00 |
| WP_234512204.1 | transglycosylase domain-containing protein [Streptomyces glo...
| 3030 | 0.0e+00 |
| WP_067010957.1 | transglycosylase domain-containing protein [Streptomyces cel...
| 3023 | 0.0e+00 |
| WP_055492087.1 | transglycosylase domain-containing protein [Streptomyces sp....
| 3011 | 0.0e+00 |
| WP_067046757.1 | transglycosylase domain-containing protein [Streptomyces sp....
| 3010 | 0.0e+00 |
| WP_189314596.1 | penicillin-binding protein [Streptomyces brasiliensis] >dbj
| 2995 | 0.0e+00 |
| WP_158923211.1 | transglycosylase domain-containing protein [Streptomyces bro...
| 2991 | 0.0e+00 |
| WP_189303425.1 | transglycosylase domain-containing protein [Streptomyces cin...
| 2987 | 0.0e+00 |
| WP_030606403.1 | transglycosylase domain-containing protein [Streptomyces ach...
| 2985 | 0.0e+00 |
| WP_093475973.1 | MULTISPECIES: penicillin-binding protein [unclassified Strep...
| 2985 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| membrane | 0.3039 | Seems to have no N-terminal signal seq.
|