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IDSAVERM_4593 TypeCDS
From5607216 nt length933
To5608148 aa length310
Genenth pI10.38
Definitionputative endonuclease III M.W (Da)33718
NotePF00730: HhH-GPD superfamily base excision DNA repair protein AseI frg.L
SignalP v.4.0Signal peptide | plot CategoryDNA modification & repair

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO3569 putative endonuclease4844.0e-176
sgrSGR_3332 putative endonuclease III4319.0e-155
samSAM23877_4093 Endonuclease III5140.0e+00
scabSCAB41301 putative endonuclease III5020.0e+00
saceSACE_0331 putative endonuclease III2932.0e-100
nfarnfa3480 endonuclease III3013.7e-83
mtubgi|57117142 PROBABLE ENDONUCLEASE III NTH (DNA-(APURINIC OR APYRIMIDINIC SITE)LYASE) (AP LYASE) (AP ENDONUCLEASE CLASS I) (ENDODEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC)) (DEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC)) [Mycobacterium tuberculosis H37Rv]2931.0e-80
cglugi|19551543 COG0177:Predicted EndoIII-related endonuclease [Corynebacterium glutamicum]2791.4e-76
bsubBG10956 nth, jooB, ypoB; endonuclease III [EC:4.2.99.18]1661.6e-42
ecoligi|16129591 endonuclease III; DNA glycosylase/apyrimidinic (AP) lyase [Escherichia coli K12]1391.8e-34
paerPA3495 [gene=nth] [prot=endonuclease III] [comment=PA3495]1441.0e-35

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

HhH-GPD1HhH-GPD superfamily base excision DNA repair protein89-22083.01.7e-23

HHH1Helix-hairpin-helix motif153-17627.81.3e-06

EndIII_4Fe-2S1Iron-sulfur binding domain of endonuclease III241-25724.52.3e-05

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_234512188.1 endonuclease III [Streptomyces glomeratus] >lcl 12932.3e-177
PBC62468.1 endonuclease III [Streptomyces sp. Tue6028] 12884.3e-177
WP_107459571.1 endonuclease III [Streptomyces colonosanans] 12885.9e-177
OIJ89748.1 endonuclease III [Streptomyces colonosanans] 12906.4e-177
WP_095935658.1 endonuclease III [Streptomyces sp. Tue6028] 12831.1e-176
WP_229911559.1 endonuclease III [Streptomyces aurantiogriseus] 12751.8e-175
GGR63407.1 hypothetical protein GCM10010251_95080 [Streptomyces aurantiogri... 12772.0e-175
WP_161240078.1 endonuclease III [Streptomyces sp. SID2888] >gb 12766.6e-175
WP_203690121.1 endonuclease III [Streptomyces sp. SID12488] 12807.1e-175
AJE41748.1 endonuclease [Streptomyces nodosus] 12777.8e-175

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.2793 Seems to have no N-terminal signal seq.