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IDSAVERM_4669 TypeCDS
From5694881 nt length612
To5694270 aa length203
GenefolK pI4.45
Definitionputative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase M.W (Da)22108
NotePF01288: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) AseI frg.R
SignalP v.4.0Non-secretory protein | plot Categorymetabolism of coenzymes & prosthetic groups

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO3401 putative hydroxymethyldihydropteridine pyrophosphokinase3501.0e-125
sgrSGR_4091 putative 2-amino-4-hydroxy-6-hydroxymethyldihydr opteridine pyrophosphokinase3473.0e-124
samSAM23877_4162 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase3582.0e-128
scabSCAB39751 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase3445.0e-123
saceSACE_0400 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase1203.0e-35
nfarnfa4020 folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase1191.4e-28
mtubgi|15610742 2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDI NE PYROPHOSPHOKINASE FOLK (7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN-PYROPHOSPHOKINASE) (HPPK) (6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE) (PPPK) (2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE DIPHOSPHOKINASE) (7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN-DIPHOSPHOKINASE) (6-HYDROXYMETHYL-7,8-DIHYDROPTERIN DIPHOSPHOKINASE) [Mycobacterium tuberculosis H37Rv]1191.9e-28
cglugi|19553886 COG0801:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Corynebacterium glutamicum]1197.8e-29
bsubBG10142 folK; 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase [EC:2.7.6.3]976.8e-22
ecoligi|16128135 7,8-dihydro-6-hydroxymethylpterin- pyrophosphokinase [Escherichia coli K12]1038.2e-24
paerPA4728 [gene=folK] [prot=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase] [comment=PA4728]1221.8e-29

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

HPPK17,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)39-169128.41.5e-37

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_189188544.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphok... 8261.4e-110
WP_095935719.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphok... 8155.5e-109
WP_028799070.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphok... 8131.1e-108
WP_152865886.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphok... 8086.0e-108
WP_134035001.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphok... 8087.3e-108
WP_112439079.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphok... 8071.2e-107
WP_171109694.1 MULTISPECIES: 2-amino-4-hydroxy-6-hydroxymethyldihydropterid... 8061.3e-107
WP_218513939.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphok... 8051.8e-107
WP_131564153.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphok... 8052.1e-107
WP_053756465.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphok... 8034.1e-107

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.0232 Seems to have no N-terminal signal seq.