| ID | SAVERM_4672
| Type | CDS
|
| From | 5696946
| nt length | 933
|
| To | 5696014
| aa length | 310
|
| Gene | folP2
| pI | 5.41
|
| Definition | putative dihydropteroate synthase
| M.W (Da) | 32051
|
| Note | PF00809: Pterin binding enzyme
| AseI frg. | R
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of coenzymes & prosthetic groups
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO3398 putative dihydropteroate synthase | 427 | 9.0e-153
|
| sgr | SGR_4094 putative dihydropteroate synthase | 414 | 1.0e-147
|
| sam | SAM23877_4165 Dihydropteroate synthase 1 | 442 | 2.0e-158
|
| scab | SCAB39721 putative dihydropteroate synthase | 459 | 2.0e-165
|
| sace | SACE_0398 7,8-dihydropteroate synthase (partial match) | 266 | 1.0e-89
|
| nfar | nfa4000 folP dihydropteroate synthase | 286 | 1.6e-78
|
| mtub | gi|57117134 DIHYDROPTEROATE SYNTHASE 1 FOLP (DHPS 1) (DIHYDROPTEROATE PYROPHOSPHORYLASE 1) (DIHYDROPTEROATE DIPHOSPHORYLASE 1) [Mycobacterium tuberculosis H37Rv] | 281 | 3.0e-77
|
| cglu | gi|19553888 COG0294:Dihydropteroate synthase and related enzymes [Corynebacterium glutamicum] | 243 | 6.4e-66
|
| bsub | BG10140 sul; dihydropteroate synthase [EC:2.5.1.15] | 203 | 1.2e-53
|
| ecoli | gi|49176323 7,8-dihydropteroate synthase [Escherichia coli K12] | 187 | 5.9e-49
|
| paer | PA4750 [gene=folP] [prot=dihydropteroate synthase] [comment=PA4750] | 197 | 1.0e-51
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| Pterin_bind | 1 | Pterin binding enzyme | 22-267 | 285.8 | 2.8e-85
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_099504904.1 | MULTISPECIES: dihydropteroate synthase [Streptomyces] >gb
| 895 | 6.4e-118 |
| WP_151477690.1 | dihydropteroate synthase [Streptomyces albicerus]
| 889 | 4.8e-117 |
| WP_189773238.1 | dihydropteroate synthase [Streptomyces tauricus]
| 889 | 7.3e-117 |
| WP_217458908.1 | dihydropteroate synthase [Streptomyces sp. BV286] >lcl
| 887 | 9.3e-117 |
| WP_119101430.1 | dihydropteroate synthase [Streptomyces sporangiiformans] >lc...
| 887 | 1.0e-116 |
| WP_107022333.1 | dihydropteroate synthase [Streptomyces dioscori] >gb
| 887 | 1.5e-116 |
| WP_138048805.1 | dihydropteroate synthase [Streptomyces montanus] >lcl
| 885 | 1.6e-116 |
| WP_210881809.1 | dihydropteroate synthase [Streptomyces sp. BH-SS-21] >lcl
| 886 | 1.8e-116 |
| WP_079103474.1 | MULTISPECIES: dihydropteroate synthase [Streptomyces auranti...
| 885 | 1.9e-116 |
| WP_101399895.1 | MULTISPECIES: dihydropteroate synthase [Streptomyces] >gb
| 882 | 4.0e-116 |
PSORT result
| Localization | Certainty | PSORT said
|
| membrane | 0.1107 | Seems to have an uncleavable N-term signal seq
|