| ID | SAVERM_4724
| Type | CDS
|
| From | 5756668
| nt length | 810
|
| To | 5757477
| aa length | 269
|
| Gene | proC
| pI | 6.31
|
| Definition | putative pyrroline-5-carboxylate reductase
| M.W (Da) | 28158
|
| Note | PF03807: NADP oxidoreductase coenzyme F420-dependent
| AseI frg. | R
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of amino acids & related molecules
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO3337 pyrroline-5-carboxylate reductase | 481 | 1.0e-174
|
| sgr | SGR_4141 putative pyrroline-5-carboxylate reductase | 425 | 8.0e-153
|
| sam | SAM23877_4223 Pyrroline-5-carboxylate reductase | 486 | 6.0e-177
|
| scab | SCAB39221 putative pyrroline-5-carboxylate reductase | 481 | 7.0e-175
|
| sace | SACE_6959 pyrroline-5-carboxylate reductase | 320 | 3.0e-111
|
| nfar | nfa51770 proC pyrroline-5-carboxylate reductase | 232 | 2.3e-62
|
| mtub | gi|15607641 pyrroline-5-carboxylate reductase [Mycobacterium tuberculosis H37Rv] | 198 | 2.8e-52
|
| cglu | gi|19551656 COG0345:Pyrroline-5-carboxylate reductase [Corynebacterium glutamicum] | 218 | 1.8e-58
|
| bsub | BG11049 proH, yoxE; pyrroline-5-carboxylate reductase [EC:1.5.1.2] | 173 | 8.4e-45
|
| ecoli | gi|16128371 pyrroline-5-carboxylate reductase [Escherichia coli K12] | 166 | 1.2e-42
|
| paer | PA0393 [gene=proC] [prot=pyrroline-5-carboxylate reductase] [comment=PA0393] | 182 | 2.1e-47
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| P5CR_dimer | 1 | Pyrroline-5-carboxylate reductase dimerisation | 160-264 | 130.5 | 2.3e-38
|
| F420_oxidored | 1 | NADP oxidoreductase coenzyme F420-dependent | 4-97 | 77.6 | 7.8e-22
|
| NAD_binding_2 | 1 | NAD binding domain of 6-phosphogluconate dehydrogenase | 4-95 | 27.5 | 2.8e-06
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_055618632.1 | pyrroline-5-carboxylate reductase [Streptomyces phaeochromog...
| 1212 | 2.6e-167 |
| WP_189843121.1 | pyrroline-5-carboxylate reductase [Streptomyces umbrinus] >d...
| 1208 | 1.1e-166 |
| WP_143640475.1 | pyrroline-5-carboxylate reductase [Streptomyces sp. IB201691...
| 1208 | 1.2e-166 |
| WP_200397506.1 | pyrroline-5-carboxylate reductase [Streptomyces sp. ZYC-3] >...
| 1207 | 1.5e-166 |
| WP_189773307.1 | pyrroline-5-carboxylate reductase [Streptomyces tauricus] >d...
| 1203 | 7.5e-166 |
| WP_043687991.1 | pyrroline-5-carboxylate reductase [Streptomyces xylophagus]
| 1201 | 1.5e-165 |
| WP_099506242.1 | MULTISPECIES: pyrroline-5-carboxylate reductase [Streptomyce...
| 1201 | 1.6e-165 |
| WP_069779432.1 | pyrroline-5-carboxylate reductase [Streptomyces fodineus] >g...
| 1200 | 1.9e-165 |
| WP_190202759.1 | pyrroline-5-carboxylate reductase [Streptomyces fumanus] >db...
| 1199 | 3.0e-165 |
| WP_037850395.1 | pyrroline-5-carboxylate reductase [Streptomyces sp. NRRL S-3...
| 1198 | 3.7e-165 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.0480 | Seems to have no N-terminal signal seq.
|