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IDSAVERM_4824 TypeCDS
From5864704 nt length744
To5865447 aa length247
GenepilD pI7.84
Definitionputative leader peptidase (prepilin peptidase) / N-methyltransferase M.W (Da)25421
NoteType II secretion system, PF01478: Type IV leader peptidase family AseI frg.I
SignalP v.4.0Non-secretory protein | plot Categoryprotein secretion

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO4549 putative type IV peptidase2612.0e-88
sgrSGR_2510 putative type IV peptidase1931.0e-61
samSAM23877_4372 Type IV peptidase2264.0e-75
scabSCAB38201 putative leader peptidase (prepilin peptidase) 2297.0e-76
nfarnfa36340 peptidase761.8e-15
mtubgi|15609688 hypothetical protein Rv2551c [Mycobacterium tuberculosis H37Rv]701.3e-13
cglugi|19552836 COG1989:Signal peptidase, cleaves prepilin-like proteins [Corynebacterium glutamicum]645.1e-12
bsubBG10323 comC; late competence protein required for processing and translocation of ComGC, ComGD, ComGE, ComGG [leader peptidase (prepilin peptidase) / N-methyltransferase] [EC:3.4.99.- 2.1.1.-]638.4e-12
ecoligi|16131214 bifunctional prepilin peptidase: leader peptidase; N-methyltransferase; part of general secretion pathway (GSP) [Escherichia coli K12]692.3e-13
paerPA4528 [gene=pilD] [prot=type 4 prepilin peptidase PilD] [comment=PA4528]793.0e-16

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

Peptidase_A241Type IV leader peptidase family101-21266.03.2e-18

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_202498322.1 prepilin peptidase [Streptomyces sp. SID5469] 5171.6e-62
4322.6e-49
WP_103548312.1 A24 family peptidase [Streptomyces populi] >gb 4285.2e-49
WP_192582484.1 A24 family peptidase [Streptomyces triticiradicis] 4261.0e-48
WP_059130196.1 A24 family peptidase [Streptomyces sp. NRRL F-5122] >gb 4154.8e-47
4147.4e-47
WP_037627518.1 A24 family peptidase [Streptomyces aureus] 4121.4e-46
WP_220296459.1 A24 family peptidase [Streptomyces sp. MBT84] 4068.8e-46
WP_052454191.1 A24 family peptidase [Streptomyces nodosus] >lcl 4033.0e-45
WP_043448998.1 A24 family peptidase [Streptomyces nodosus] >gb 4033.0e-45

PSORT result

LocalizationCertaintyPSORT said
membrane0.5034 Seems to have no N-terminal signal seq.