| ID | SAVERM_5149
| Type | CDS
|
| From | 6253610
| nt length | 1146
|
| To | 6254755
| aa length | 381
|
| Gene | hpd
| pI | 5.4
|
| Definition | 4-hydroxyphenylpyruvate dioxygenase
| M.W (Da) | 41863
|
| Note | ochronotic pigment biosynthesis, PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
| AseI frg. | B
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | antibiotic production
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO2927 putative 4-hydroxyphenylpyruvate dioxygenase | 734 | 0.0e+00
|
| sgr | SGR_4612 4-hydroxyphenylpyruvate dioxygenase | 717 | 0.0e+00
|
| sam | SAM23877_2965 4-hydroxyphenylpyruvate dioxygenase | 744 | 0.0e+00
|
| scab | SCAB56371 putative 4-hydroxyphenylpyruvate dioxygenase | 740 | 0.0e+00
|
| sace | SACE_0905 4-hydroxyphenylpyruvate dioxygenase | 510 | 0.0e+00
|
| nfar | nfa50810 4-hydroxyphenylpyruvate dioxygenase | 452 | 1.7e-128
|
| bsub | BG11283 yqbL; unknown | 27 | 1.5e+00
|
| ecoli | gi|49176119 tagaturonate reductase [Escherichia coli K12] | 30 | 2.7e-01
|
| paer | PA0865 [gene=hpd] [prot=4-hydroxyphenylpyruvate dioxygenase] [comment=PA0865] | 176 | 2.4e-45
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| Glyoxalase | 2 | Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily | 22-129, 185-335 | 84.6 | 5.7e-24
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_053749295.1 | 4-hydroxyphenylpyruvate dioxygenase [Streptomyces sp. MMG153...
| 1968 | 0.0e+00 |
| WP_109498510.1 | 4-hydroxyphenylpyruvate dioxygenase [Streptomyces sp. Act143...
| 1966 | 0.0e+00 |
| WP_053191144.1 | 4-hydroxyphenylpyruvate dioxygenase [Streptomyces resistomyc...
| 1965 | 0.0e+00 |
| WP_151470918.1 | 4-hydroxyphenylpyruvate dioxygenase [Streptomyces triticirad...
| 1962 | 0.0e+00 |
| WP_208784701.1 | 4-hydroxyphenylpyruvate dioxygenase [Streptomyces griseorubi...
| 1962 | 0.0e+00 |
| WP_150471256.1 | 4-hydroxyphenylpyruvate dioxygenase [Streptomyces galilaeus]...
| 1962 | 0.0e+00 |
| WP_004000901.1 | 4-hydroxyphenylpyruvate dioxygenase [Streptomyces viridochro...
| 1962 | 0.0e+00 |
| WP_095748740.1 | 4-hydroxyphenylpyruvate dioxygenase [Streptomyces sp. SA15] ...
| 1961 | 0.0e+00 |
| WP_007382375.1 | MULTISPECIES: 4-hydroxyphenylpyruvate dioxygenase [Streptomy...
| 1957 | 0.0e+00 |
| WP_059210079.1 | 4-hydroxyphenylpyruvate dioxygenase [Streptomyces canus] >gb...
| 1957 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.1894 | Seems to have no N-terminal signal seq.
|