| ID | SAVERM_5276
| Type | CDS
|
| From | 6392598
| nt length | 948
|
| To | 6391651
| aa length | 315
|
| Gene | hmgL
| pI | 5.18
|
| Definition | putative hydroxymethylglutaryl-CoA lyase
| M.W (Da) | 33523
|
| Note | PF00682: HMGL-like
| AseI frg. | B
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | specific pathways
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO2778 hmgL hydroxymethylglutaryl-CoA lyase | 542 | 0.0e+00
|
| sgr | SGR_4757 putative hydroxymethylglutaryl-CoA lyase | 505 | 0.0e+00
|
| sam | SAM23877_2813 Hydroxymethylglutaryl-CoA lyase YngG | 539 | 0.0e+00
|
| scab | SCAB58011 putative hydroxymethylglutaryl-CoA lyase | 533 | 0.0e+00
|
| sace | SACE_6499 hydroxymethylglutaryl-CoA lyase | 397 | 1.0e-140
|
| nfar | nfa46700 hydroxymethylglutaryl-CoA lyase | 145 | 4.5e-36
|
| cglu | gi|19552297 COG3238:Uncharacterized BCR [Corynebacterium glutamicum] | 32 | 3.0e-02
|
| bsub | BG13458 yngG; similar to hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] | 261 | 3.8e-71
|
| paer | PA2011 [gene=PA2011] [prot=hydroxymethylglutaryl-CoA lyase] [comment=PA2011] | 257 | 8.4e-70
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| HMGL-like | 1 | HMGL-like | 20-291 | 169.7 | 8.3e-50
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_217566626.1 | hydroxymethylglutaryl-CoA lyase [Streptomyces sp. GbtcB7]
| 1500 | 0.0e+00 |
| WP_189184894.1 | hydroxymethylglutaryl-CoA lyase [Streptomyces albiflavescens...
| 1495 | 0.0e+00 |
| WP_168491817.1 | MULTISPECIES: hydroxymethylglutaryl-CoA lyase [Streptomyces]...
| 1494 | 0.0e+00 |
| WP_143613438.1 | MULTISPECIES: hydroxymethylglutaryl-CoA lyase [unclassified ...
| 1494 | 0.0e+00 |
| WP_054232881.1 | MULTISPECIES: hydroxymethylglutaryl-CoA lyase [unclassified ...
| 1493 | 0.0e+00 |
| WP_143608183.1 | MULTISPECIES: hydroxymethylglutaryl-CoA lyase [unclassified ...
| 1492 | 0.0e+00 |
| WP_075029219.1 | hydroxymethylglutaryl-CoA lyase [Streptomyces mirabilis] >em...
| 1489 | 0.0e+00 |
| QIY96079.1 | hydroxymethylglutaryl-CoA lyase [Streptomyces sp. S1D4-11]
| 1488 | 0.0e+00 |
| WP_168528249.1 | hydroxymethylglutaryl-CoA lyase [Streptomyces sp. RPA4-2] >g...
| 1488 | 0.0e+00 |
| WP_181651250.1 | hydroxymethylglutaryl-CoA lyase [Streptomyces sp. WAC00263] ...
| 1487 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| membrane | 0.1595 | Seems to have no N-terminal signal seq.
|