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IDSAVERM_5669 TypeCDS
From6857552 nt length1596
To6855957 aa length531
Genezmp6 pI6.45
Definitionputative griselysin (secreted neutral zinc metalloprotease) M.W (Da)55092
NotePF02868: Thermolysin metallopeptidase, alpha-helical domain AseI frg.B
SignalP v.4.0Signal peptide | plot Categoryprotein modification


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO2474 putative metalloproteinase8010.0e+00
samSAM23877_2529 Metalloproteinase7570.0e+00
scabSCAB87901 putative neutral zinc metalloprotease, secreted7370.0e+00
bsubBG10691 nprB; extracellular neutral protease B [EC:3.4.24.-]2001.9e-52

*coel, Streptomyces coelicolor A3(2); sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; bsub, Bacillus subtilis;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

Peptidase_M4_C1Thermolysin metallopeptidase, alpha-helical domain355-530191.11.2e-56

Peptidase_M41Thermolysin metallopeptidase, catalytic domain194-352171.02e-50

FTP1Fungalysin/Thermolysin Propeptide Motif52-9248.16.9e-13

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_202498452.1 M4 family metallopeptidase [Streptomyces sp. SID5469] 24410.0e+00
WP_234512784.1 M4 family metallopeptidase [Streptomyces glomeratus] >lcl 22230.0e+00
WP_189185229.1 M4 family metallopeptidase [Streptomyces albiflavescens] >db... 22130.0e+00
WP_095854802.1 M4 family metallopeptidase [Streptomyces sp. Ag82_O1-15] >gb... 21770.0e+00
WP_097284630.1 MULTISPECIES: M4 family metallopeptidase [unclassified Strep... 21750.0e+00
WP_220294178.1 M4 family metallopeptidase [Streptomyces sp. MBT84] >lcl 21750.0e+00
WP_067369719.1 M4 family metallopeptidase [Streptomyces olivochromogenes] >... 21750.0e+00
WP_075026752.1 M4 family metallopeptidase [Streptomyces mirabilis] >emb 21720.0e+00
WP_097226006.1 M4 family metallopeptidase [Streptomyces sp. OV198] >emb 21710.0e+00
WP_143613318.1 MULTISPECIES: M4 family metallopeptidase [unclassified Strep... 21710.0e+00

PSORT result

LocalizationCertaintyPSORT said
outside0.3000 Seems to have a cleavable N-term signal seq.