| ID | SAVERM_5943
| Type | CDS
|
| From | 7155241
| nt length | 864
|
| To | 7154378
| aa length | 287
|
| Gene | panB
| pI | 5.67
|
| Definition | putative 3-methyl-2-oxobutanoate hydroxymethyltransferase
| M.W (Da) | 30365
|
| Note | PF02548: Ketopantoate hydroxymethyltransferase
| AseI frg. | F
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of coenzymes & prosthetic groups
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO2256 3-methyl-2-oxobutanoate hydroxymethyltransferase | 542 | 0.0e+00
|
| sgr | SGR_5253 putative 3-methyl-2-oxobutanoate hydroxymethyltransferase | 489 | 1.0e-177
|
| sam | SAM23877_2335 3-methyl-2-oxobutanoate hydroxymethyltransferase | 548 | 0.0e+00
|
| scab | SCAB66381 putative 3-methyl-2-oxobutanoate hydroxymethyltransferase | 550 | 0.0e+00
|
| sace | SACE_1604 3-methyl-2-oxobutanoate hydroxymethyltransferase | 307 | 7.0e-106
|
| nfar | nfa16500 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase | 305 | 2.3e-84
|
| mtub | gi|15609362 3-methyl-2-oxobutanoate hydroxymethyltransferase [Mycobacterium tuberculosis H37Rv] | 306 | 1.4e-84
|
| cglu | gi|19551365 COG0413:Ketopantoate hydroxymethyltransferase [Corynebacterium glutamicum] | 261 | 2.1e-71
|
| bsub | BG11519 panB; ketopantoate hydroxymethyltransferase [EC:2.1.2.11] | 210 | 8.8e-56
|
| ecoli | gi|16128127 3-methyl-2-oxobutanoate hydroxymethyltransferase [Escherichia coli K12] | 213 | 1.2e-56
|
| paer | PA1598 [gene=PA1598] [prot=conserved hypothetical protein] [comment=PA1598] | 217 | 8.6e-58
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| Pantoate_transf | 1 | Ketopantoate hydroxymethyltransferase | 25-280 | 358.4 | 1.9e-107
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_037669190.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase [Streptomyc...
| 1393 | 0.0e+00 |
| WP_151482216.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase [Streptomyc...
| 1384 | 0.0e+00 |
| WP_141361460.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase [Streptomyc...
| 1382 | 0.0e+00 |
| WP_045562832.1 | MULTISPECIES: 3-methyl-2-oxobutanoate hydroxymethyltransfera...
| 1382 | 0.0e+00 |
| WP_220649306.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase [Streptomyc...
| 1382 | 0.0e+00 |
| WP_030341087.1 | MULTISPECIES: 3-methyl-2-oxobutanoate hydroxymethyltransfera...
| 1382 | 0.0e+00 |
| WP_053190733.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase [Streptomyc...
| 1382 | 0.0e+00 |
| WP_067014460.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase [Streptomyc...
| 1381 | 0.0e+00 |
| WP_189940357.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase [Streptomyc...
| 1379 | 0.0e+00 |
| WP_210586872.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase [Streptomyc...
| 1378 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| membrane | 0.1362 | Seems to have no N-terminal signal seq.
|