| ID | SAVERM_6009
| Type | CDS
|
| From | 7236458
| nt length | 987
|
| To | 7235472
| aa length | 328
|
| Gene | lipA
| pI | 5.96
|
| Definition | putative lipoic acid synthetase
| M.W (Da) | 36964
|
| Note | PF04055: Radical SAM superfamily
| AseI frg. | F
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of coenzymes & prosthetic groups
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO2194 putative lipoic acid synthetase | 619 | 0.0e+00
|
| sgr | SGR_5319 putative lipoic acid synthetase | 591 | 0.0e+00
|
| sam | SAM23877_2289 lipoate synthase | 625 | 0.0e+00
|
| scab | SCAB66921 putative lipoic acid synthetase | 619 | 0.0e+00
|
| sace | SACE_1626 putative lipoic acid synthetase | 490 | 9.0e-177
|
| nfar | nfa16860 lipA lipoic acid synthetase | 494 | 3.2e-141
|
| mtub | gi|15609355 lipoyl synthase [Mycobacterium tuberculosis H37Rv] | 473 | 9.9e-135
|
| cglu | gi|19553410 COG0320:Lipoate synthase [Corynebacterium glutamicum] | 440 | 5.0e-125
|
| bsub | BG14038 lipA, yutB; lipoic acid synthetase | 251 | 5.4e-68
|
| ecoli | gi|16128611 lipoyl synthase [Escherichia coli K12] | 243 | 1.3e-65
|
| paer | PA3996 [gene=lipA] [prot=lipoate synthase] [comment=PA3996] | 241 | 5.1e-65
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| Radical_SAM | 1 | Radical SAM superfamily | 82-240 | 46.4 | 5.1e-12
|
| LIAS_N | 1 | N-terminal domain of lipoyl synthase of Radical_SAM family | 25-61 | 30.6 | 3.3e-07
|
BLAST search result (top 10 hits)
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.4577 | Seems to have no N-terminal signal seq.
|