| ID | SAVERM_6026
| Type | CDS
|
| From | 7256993
| nt length | 783
|
| To | 7256211
| aa length | 260
|
| Gene | cobS
| pI | 9.89
|
| Definition | putative cobalamin (5’-phosphate) synthase
| M.W (Da) | 25667
|
| Note | cobalamin biosynthesis, PF02654: Cobalamin-5-phosphate synthase
| AseI frg. | F
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of coenzymes & prosthetic groups
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO2177 putative cobalamin (5'-phosphate) synthase | 248 | 2.0e-83
|
| sgr | SGR_5332 putative cobalamin 5'-phosphate synthase | 224 | 4.0e-74
|
| sam | SAM23877_2272 Cobalamin synthase | 254 | 6.0e-86
|
| scab | SCAB67091 putative cobalamin (5'-phosphate) synthase | 234 | 7.0e-78
|
| sace | SACE_1649 putative cobalamin 5'-phosphate synthase | 129 | 3.0e-37
|
| nfar | nfa16990 cobS cobalamin 5'-phosphate synthase | 169 | 2.3e-43
|
| mtub | gi|15609345 cobalamin synthase [Mycobacterium tuberculosis H37Rv] | 140 | 8.6e-35
|
| cglu | gi|19553403 COG0368:Cobalamin-5-phosphate synthase [Corynebacterium glutamicum] | 88 | 2.1e-19
|
| ecoli | gi|16129933 cobalamin synthase [Escherichia coli K12] | 92 | 2.0e-20
|
| paer | PA1281 [gene=cobV] [prot=cobalamin (5'-phosphate) synthase] [comment=PA1281] | 93 | 1.6e-20
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| CobS | 1 | Cobalamin-5-phosphate synthase | 13-254 | 155.5 | 1.8e-45
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_189724619.1 | adenosylcobinamide-GDP ribazoletransferase [Streptomyces pur...
| 433 | 2.7e-49 |
| WP_099500903.1 | MULTISPECIES: adenosylcobinamide-GDP ribazoletransferase [St...
| 428 | 1.4e-48 |
| WP_095855092.1 | MULTISPECIES: adenosylcobinamide-GDP ribazoletransferase [un...
| 417 | 5.2e-47 |
| WP_075026454.1 | MULTISPECIES: adenosylcobinamide-GDP ribazoletransferase [St...
| 417 | 6.4e-47 |
| WP_168490665.1 | MULTISPECIES: adenosylcobinamide-GDP ribazoletransferase [St...
| 416 | 7.4e-47 |
| WP_059205978.1 | adenosylcobinamide-GDP ribazoletransferase [Streptomyces can...
| 414 | 1.5e-46 |
| WP_189190476.1 | adenosylcobinamide-GDP ribazoletransferase [Streptomyces alb...
| 415 | 1.6e-46 |
| WP_062037711.1 | adenosylcobinamide-GDP ribazoletransferase [Streptomyces can...
| 414 | 1.6e-46 |
| WP_067363508.1 | adenosylcobinamide-GDP ribazoletransferase [Streptomyces oli...
| 414 | 1.8e-46 |
| WP_181651588.1 | adenosylcobinamide-GDP ribazoletransferase [Streptomyces sp....
| 413 | 2.5e-46 |
PSORT result
| Localization | Certainty | PSORT said
|
| membrane | 0.5161 | Seems to have no N-terminal signal seq.
|