| ID | SAVERM_6032
| Type | CDS
|
| From | 7264525
| nt length | 1320
|
| To | 7263206
| aa length | 439
|
| Gene | cobU
| pI | 5.48
|
| Definition | putative adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase
| M.W (Da) | 45559
|
| Note | cobalamin biosynthesis, PF02283: Cobinamide kinase / cobinamide phosphate guanyltransferase
| AseI frg. | F
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | miscellaneous
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO2173 putative multifunctional enzyme | 623 | 0.0e+00
|
| sgr | SGR_5336 putative adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase | 531 | 0.0e+00
|
| sam | SAM23877_2268 putative adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase | 607 | 0.0e+00
|
| scab | SCAB67141 putative adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase | 610 | 0.0e+00
|
| sace | SACE_1651 cobinamide kinase / conamide phosphate guanylyltransferase | 137 | 2.0e-39
|
| nfar | nfa17010 cobU cobinamide kinase/cobinamide phosphate guanylyltransferase | 140 | 2.9e-34
|
| mtub | gi|15607395 PROBABLE BIFUNCTIONAL COBALAMIN BIOSYNTHESIS PROTEIN COBU: COBINAMIDE KINASE + COBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE [Mycobacterium tuberculosis H37Rv] | 135 | 5.4e-33
|
| cglu | gi|19553401 COG2087:Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase [Corynebacterium glutamicum] | 129 | 2.1e-31
|
| ecoli | gi|16129934 adenosylcobinamide kinase [Escherichia coli K12] | 103 | 2.9e-23
|
| paer | PA1278 [gene=cobP] [prot=cobinamide kinase] [comment=PA1278] | 112 | 6.7e-26
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| CobU | 1 | Cobinamide kinase / cobinamide phosphate guanyltransferase | 263-435 | 170.5 | 2.2e-50
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_237529632.1 | bifunctional adenosylcobinamide kinase/adenosylcobinamide-ph...
| 1570 | 0.0e+00 |
| WP_189190470.1 | bifunctional adenosylcobinamide kinase/adenosylcobinamide-ph...
| 1427 | 0.0e+00 |
| WP_151483994.1 | bifunctional adenosylcobinamide kinase/adenosylcobinamide-ph...
| 1423 | 0.0e+00 |
| GGX66139.1 | adenosylcobinamide kinase/adenosylcobinamide phosphate guanyltra...
| 1422 | 0.0e+00 |
| WP_200398758.1 | bifunctional adenosylcobinamide kinase/adenosylcobinamide-ph...
| 1415 | 0.0e+00 |
| WP_055618418.1 | bifunctional adenosylcobinamide kinase/adenosylcobinamide-ph...
| 1413 | 0.0e+00 |
| WP_223179809.1 | bifunctional adenosylcobinamide kinase/adenosylcobinamide-ph...
| 1410 | 0.0e+00 |
| WP_190228218.1 | bifunctional adenosylcobinamide kinase/adenosylcobinamide-ph...
| 1409 | 0.0e+00 |
| WP_143631138.1 | bifunctional adenosylcobinamide kinase/adenosylcobinamide-ph...
| 1409 | 0.0e+00 |
| WP_148013644.1 | bifunctional adenosylcobinamide kinase/adenosylcobinamide-ph...
| 1408 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.1778 | Seems to have no N-terminal signal seq.
|