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IDSAVERM_6100 TypeCDS
From7336079 nt length924
To7337002 aa length307
GenemetF pI6.1
Definitionputative 5,10-methylenetetrahydrofolate reductase M.W (Da)33430
NotePF02219: Methylenetetrahydrofolate reductase AseI frg.F
SignalP v.4.0Non-secretory protein | plot Categorymetabolism of coenzymes & prosthetic groups

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO2103 5,10-methylenetetrahydrofolate reductase5830.0e+00
sgrSGR_5399 "putative 5,10-methylenetetrahydrofolate reductase"5460.0e+00
samSAM23877_2196 5, 10-methylenetetrahydrofolate reductase5910.0e+00
scabSCAB67791 putative 5,10-methylenetetrahydrofolate reductase5430.0e+00
saceSACE_3895 5,10-methylenetetrahydrofolate reductase3561.0e-124
nfarnfa17400 metF 5,10-methylenetetrahydrofolate reductase3001.4e-82
cglugi|19553373 COG0685:5,10-methylenetetrahydrofolate reductase [Corynebacterium glutamicum]2283.6e-61
ecoligi|16131779 5,10-methylenetetrahydrofolate reductase [Escherichia coli K12]1862.2e-48
paerPA0430 [gene=metF] [prot=5,10-methylenetetrahydrofolate reductase] [comment=PA0430]2062.2e-54

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; cglu, Corynebacterium glutamicum; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

MTHFR1Methylenetetrahydrofolate reductase16-300365.61.6e-109

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_126271406.1 methylenetetrahydrofolate reductase [NAD(P)H] [Streptomyces ... 15650.0e+00
WP_171144427.1 methylenetetrahydrofolate reductase [NAD(P)H] [Streptomyces ... 15600.0e+00
WP_189321225.1 methylenetetrahydrofolate reductase [NAD(P)H] [Streptomyces ... 15580.0e+00
WP_165266080.1 methylenetetrahydrofolate reductase [NAD(P)H] [Streptomyces ... 15580.0e+00
WP_097262956.1 methylenetetrahydrofolate reductase [NAD(P)H] [Streptomyces ... 15580.0e+00
WP_232025036.1 methylenetetrahydrofolate reductase [NAD(P)H] [Streptomyces ... 15560.0e+00
WP_208781590.1 methylenetetrahydrofolate reductase [NAD(P)H] [Streptomyces ... 15560.0e+00
WP_164427074.1 methylenetetrahydrofolate reductase [NAD(P)H] [Streptomyces ... 15550.0e+00
WP_200416952.1 methylenetetrahydrofolate reductase [NAD(P)H] [Streptomyces ... 15540.0e+00
WP_059197549.1 methylenetetrahydrofolate reductase [NAD(P)H] [Streptomyces ... 15540.0e+00

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.3018 Seems to have no N-terminal signal seq.