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IDSAVERM_6117 TypeCDS
From7356881 nt length1521
To7358401 aa length506
GenemurE pI5.06
Definitionputative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase M.W (Da)53261
NotePF01225: Mur ligase family, catalytic domain AseI frg.F
SignalP v.4.0Non-secretory protein | plot Categorycell wall

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO2089 putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase8190.0e+00
sgrSGR_5416 "putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase"7580.0e+00
samSAM23877_2180 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase8200.0e+00
scabSCAB67961 putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase8560.0e+00
saceSACE_5856 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diami ligase4001.0e-135
nfarnfa17610 murE UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase4631.7e-131
mtubgi|15609295 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium tuberculosis H37Rv]4292.1e-121
cglugi|19553363 COG0769:UDP-N-acetylmuramyl tripeptide synthase [Corynebacterium glutamicum]3791.4e-106
bsubBG10223 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]3354.8e-93
ecoligi|16128078 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Escherichia coli K12]2571.1e-69
paerPA4417 [gene=murE] [prot=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase] [comment=PA4417]3001.6e-82

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

Mur_ligase_M1Mur ligase middle domain123-323174.32.5e-51

Mur_ligase_C1Mur ligase family, glutamate ligase domain344-42873.71e-20

Mur_ligase1Mur ligase family, catalytic domain34-10948.01.1e-12

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_202498525.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimela... 21450.0e+00
WP_189187795.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimela... 21050.0e+00
GGN69721.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate l... 21020.0e+00
WP_028803197.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimela... 21010.0e+00
WP_041822048.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimela... 20960.0e+00
WP_143605361.1 MULTISPECIES: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6... 20940.0e+00
NEB34947.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate li... 20930.0e+00
20910.0e+00
WP_075026393.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimela... 20900.0e+00
WP_095933711.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimela... 20900.0e+00

PSORT result

LocalizationCertaintyPSORT said
membrane0.1404 Seems to have a cleavable N-term signal seq.