-- | --

IDSAVERM_6118 TypeCDS
From7358406 nt length1416
To7359821 aa length471
GenemurF pI4.83
Definitionputative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase M.W (Da)48845
NotePF01225: Mur ligase family, catalytic domain AseI frg.F
SignalP v.4.0Non-secretory protein | plot Categorycell wall

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO2088 putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- D-alanyl-alanyl ligase8270.0e+00
sgrSGR_5417 "putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2 ,6-diaminopimelate-D-alanyl-D-alanine ligase"7120.0e+00
samSAM23877_2179 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alan ine ligase8270.0e+00
scabSCAB67971 putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase7900.0e+00
saceSACE_5855 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase4438.0e-154
nfarnfa17620 murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase5022.4e-143
mtubgi|15609294 Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis H37Rv]4291.5e-121
cglugi|19553362 COG0770:UDP-N-acetylmuramyl pentapeptide synthase [Corynebacterium glutamicum]4091.1e-115
bsubBG12084 murF, ydbQ; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D -alanyl ligase [EC:6.3.2.15]2262.2e-60
ecoligi|16128079 D-alanine:D-alanine-adding enzyme [Escherichia coli K12]2492.1e-67
paerPA4416 [gene=murF] [prot=UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase] [comment=PA4416]2663.9e-72

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

Mur_ligase_M1Mur ligase middle domain108-297162.69.6e-48

Mur_ligase_C1Mur ligase family, glutamate ligase domain321-40074.74.8e-21

Mur_ligase1Mur ligase family, catalytic domain34-9541.89.4e-11

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_189187753.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [... 20910.0e+00
WP_125507084.1 MULTISPECIES: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al... 20820.0e+00
WP_103552139.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [... 20810.0e+00
WP_217136564.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [... 20780.0e+00
WP_057599550.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [... 20780.0e+00
WP_189717231.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [... 20770.0e+00
WP_142263784.1 MULTISPECIES: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al... 20760.0e+00
WP_020129935.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [... 20750.0e+00
WP_019067758.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [... 20740.0e+00
WP_171396730.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [... 20740.0e+00

PSORT result

LocalizationCertaintyPSORT said
outside0.3000 Seems to have a cleavable N-term signal seq.