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IDSAVERM_6158 TypeCDS
From7404535 nt length729
To7405263 aa length242
GenehisA pI4.43
Definitionputative phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase M.W (Da)25263
NoteEC:5.3.1.16, possessing TrpF function AseI frg.F
SignalP v.4.0Non-secretory protein | plot Categorymetabolism of amino acids & related molecules

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO2050 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase4551.0e-165
sgrSGR_5455 putative phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase4192.0e-151
samSAM23877_2136 Phosphoribosyl isomerase A4428.0e-161
scabSCAB68401 putative phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase4394.0e-159
saceSACE_5759 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase3331.0e-117
nfarnfa18500 hisA phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase3483.2e-97
mtubgi|15608741 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Mycobacterium tuberculosis H37Rv]3342.8e-93
cglugi|19553293 COG0106:Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase [Corynebacterium glutamicum]2999.3e-83
bsubBG12597 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]1873.7e-49
ecoligi|16129965 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Escherichia coli K12]1244.4e-30
paerPA5141 [gene=hisA] [prot=phosphoribosylformimino-5-aminoimidazole carboxamide] [comment=PA5141]1285.4e-31

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

His_biosynth1Histidine biosynthesis protein7-232211.41.1e-62

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_200686539.1 bifunctional 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)... 10336.0e-141
WP_164314644.1 bifunctional 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)... 10311.4e-140
WP_006377501.1 MULTISPECIES: bifunctional 1-(5-phosphoribosyl)-5-((5-phosph... 10311.4e-140
WP_164412820.1 bifunctional 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)... 10311.5e-140
WP_156723943.1 bifunctional 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)... 10283.3e-140
WP_058925875.1 bifunctional 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)... 10284.5e-140
WP_086771622.1 MULTISPECIES: bifunctional 1-(5-phosphoribosyl)-5-((5-phosph... 10266.5e-140
WP_200714877.1 MULTISPECIES: bifunctional 1-(5-phosphoribosyl)-5-((5-phosph... 10251.2e-139
WP_095933680.1 bifunctional 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)... 10251.2e-139
WP_067363806.1 MULTISPECIES: bifunctional 1-(5-phosphoribosyl)-5-((5-phosph... 10241.3e-139

PSORT result

LocalizationCertaintyPSORT said
membrane0.1065 Seems to have no N-terminal signal seq.