| ID | SAVERM_6170
| Type | CDS
|
| From | 7417371
| nt length | 402
|
| To | 7417772
| aa length | 133
|
| Gene | hisI
| pI | 4.68
|
| Definition | putative phosphoribosyl-AMP cyclohydrolase
| M.W (Da) | 14299
|
| Note | EC:3.5.4.19, PF01502: Phosphoribosyl-AMP cyclohydrolase
| AseI frg. | F
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of amino acids & related molecules
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO2044 putative phosphoribosyl-AMP cyclohydrolase | 218 | 2.0e-75
|
| sgr | SGR_5464 putative phosphoribosyl-AMP cyclohydrolase | 212 | 4.0e-73
|
| sam | SAM23877_2131 Phosphoribosyl-AMP cyclohydrolase | 211 | 2.0e-72
|
| scab | SCAB68441 putative phosphoribosyl-AMP cyclohydrolase | 214 | 1.0e-73
|
| sace | SACE_5755 putative phosphoribosyl-AMP cyclohydrolase | 165 | 1.0e-54
|
| nfar | nfa18540 hisI phosphoribosyl-AMP cyclohydrolase | 161 | 2.1e-41
|
| mtub | gi|57116892 phosphoribosyl-AMP cyclohydrolase [Mycobacterium tuberculosis H37Rv] | 155 | 6.8e-40
|
| cglu | gi|19553290 COG0139:Phosphoribosyl-AMP cyclohydrolase [Corynebacterium glutamicum] | 140 | 2.8e-35
|
| bsub | BG12603 hisI, hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31] | 96 | 5.6e-22
|
| ecoli | gi|16129967 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein [Escherichia coli K12] | 98 | 9.8e-23
|
| paer | PA5066 [gene=hisI] [prot=phosphoribosyl-AMP cyclohydrolase] [comment=PA5066] | 119 | 9.2e-29
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| PRA-CH | 1 | Phosphoribosyl-AMP cyclohydrolase | 43-115 | 112.4 | 6.2e-33
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_095933672.1 | phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. Tue6028]...
| 643 | 5.1e-85 |
| WP_028803151.1 | phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. 142MFCol...
| 640 | 1.3e-84 |
| WP_194080138.1 | phosphoribosyl-AMP cyclohydrolase [Streptomyces justiciae] >...
| 624 | 3.2e-82 |
|
| 624 | 4.9e-82 |
| WP_059133293.1 | MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [unclassifie...
| 623 | 5.7e-82 |
| WP_217460155.1 | phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. BV286] >...
| 620 | 1.6e-81 |
| WP_030596445.1 | phosphoribosyl-AMP cyclohydrolase [Streptomyces fulvoviolace...
| 618 | 3.6e-81 |
| WP_150950015.1 | MULTISPECIES: phosphoribosyl-AMP cyclohydrolase [Streptomyce...
| 617 | 4.4e-81 |
| WP_103815177.1 | phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. Ru62] >g...
| 617 | 5.0e-81 |
| WP_200416896.1 | phosphoribosyl-AMP cyclohydrolase [Streptomyces sp. Y2F8-2]
| 616 | 7.5e-81 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.2714 | Seems to have no N-terminal signal seq.
|