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IDSAVERM_6408 TypeCDS
From7684329 nt length1251
To7683079 aa length416
GenecobL1 pI8.26
Definitionputative precorrin-6Y C5,15-methyltransferase M.W (Da)42377
Notecobalamin biosynthesis, PF00590: Tetrapyrrole (Corrin/Porphyrin) Methylases AseI frg.S
SignalP v.4.0Non-secretory protein | plot Categorymetabolism of coenzymes & prosthetic groups


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO1856 putative methyltransferase5550.0e+00
samSAM23877_1928 15-methyltransferase5500.0e+00
saceSACE_5961 precorrin-6y C5,15-methyltransferase, subunit CbiE3246.0e-109
nfarnfa31560 cobL precorrin 6B methyltransferase1618.6e-41
mtubgi|15609209 Probable precorrin-6y methyltransferase CobL [Mycobacterium tuberculosis H37Rv]1301.6e-31
cglugi|19552699 COG2241:Precorrin-6B methylase 1 [Corynebacterium glutamicum]823.6e-17
paerPA2907 [gene=cobL] [prot=precorrin-6y-dependent methyltransferase CobL] [comment=PA2907]1524.2e-38

*coel, Streptomyces coelicolor A3(2); sam, Streptomyces ambofaciens ATCC 23877; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

TP_methylase1Tetrapyrrole (Corrin/Porphyrin) Methylases1-18773.02.9e-20

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_202498581.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subun... 14420.0e+00
WP_067364457.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cob... 12832.4e-173
WP_075026155.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cob... 12806.7e-173
WP_212727610.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subun... 12807.9e-173
QIY95091.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit Cb... 12799.4e-173
WP_217571569.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subun... 12771.9e-172
WP_095855377.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subun... 12772.3e-172
WP_190170355.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subun... 12762.7e-172
WP_097226295.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subun... 12763.0e-172
WP_097284139.1 MULTISPECIES: precorrin-6y C5,15-methyltransferase (decarbox... 12702.4e-171

PSORT result

LocalizationCertaintyPSORT said
membrane0.1001 Seems to have no N-terminal signal seq.