| ID | SAVERM_6409
| Type | CDS
|
| From | 7685150
| nt length | 825
|
| To | 7684326
| aa length | 274
|
| Gene | cobM
| pI | 6.44
|
| Definition | putative precorrin-4 C11-methyltransferase
| M.W (Da) | 29078
|
| Note | cobalamin biosynthesis, PF00590: Tetrapyrrole (Corrin/Porphyrin) Methylases
| AseI frg. | S
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of coenzymes & prosthetic groups
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO1855 putative methyltransferase | 479 | 3.0e-174
|
| sgr | SGR_3527 putative methyltransferase | 175 | 1.0e-54
|
| sam | SAM23877_1927 putative cobalt-precorrin-4 C(11)-methyltransferase | 484 | 5.0e-176
|
| scab | SCAB9861 putative precorrin-4 C11-methyltransferase | 171 | 3.0e-53
|
| sace | SACE_5962 hypothetical protein | 312 | 3.0e-104
|
| nfar | nfa50340 methyltransferase | 169 | 2.4e-43
|
| mtub | gi|15609208 Probable precorrin-4 C11-methyltransferase CobM [Mycobacterium tuberculosis H37Rv] | 183 | 9.6e-48
|
| paer | PA2948 [gene=cobM] [prot=precorrin-3 methylase] [comment=PA2948] | 181 | 8.4e-47
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| TP_methylase | 1 | Tetrapyrrole (Corrin/Porphyrin) Methylases | 8-215 | 143.7 | 6.8e-42
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_095855378.1 | MULTISPECIES: precorrin-4 C(11)-methyltransferase [unclassif...
| 1338 | 0.0e+00 |
| WP_054232273.1 | MULTISPECIES: precorrin-4 C(11)-methyltransferase [unclassif...
| 1336 | 0.0e+00 |
| WP_143607719.1 | MULTISPECIES: precorrin-4 C(11)-methyltransferase [unclassif...
| 1335 | 0.0e+00 |
| WP_143612965.1 | MULTISPECIES: precorrin-4 C(11)-methyltransferase [unclassif...
| 1335 | 0.0e+00 |
| WP_067364460.1 | precorrin-4 C(11)-methyltransferase [Streptomyces olivochrom...
| 1332 | 0.0e+00 |
| WP_217571570.1 | precorrin-4 C(11)-methyltransferase [Streptomyces sp. GbtcB7...
| 1330 | 0.0e+00 |
| WP_075026154.1 | precorrin-4 C(11)-methyltransferase [Streptomyces mirabilis]...
| 1330 | 0.0e+00 |
| WP_168490375.1 | MULTISPECIES: precorrin-4 C(11)-methyltransferase [Streptomy...
| 1324 | 0.0e+00 |
| WP_095933445.1 | precorrin-4 C(11)-methyltransferase [Streptomyces sp. Tue602...
| 1304 | 0.0e+00 |
| WP_217454321.1 | precorrin-4 C(11)-methyltransferase [Streptomyces sp. BV286]...
| 1303 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| cytoplasm | 0.0712 | Seems to have no N-terminal signal seq.
|