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IDSAVERM_6412 TypeCDS
From7688117 nt length1365
To7686753 aa length454
GenecobB pI6.35
Definitionputative cobyrinic acid a,c-diamide synthase M.W (Da)46935
Notecobalamin biosynthesis, PF01656: CobQ/CobB/MinD/ParA nucleotide binding domain AseI frg.S
SignalP v.4.0Signal peptide | plot Categorymetabolism of coenzymes & prosthetic groups

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO1852 cobyrinic acid AC-diamide synthase.7160.0e+00
sgrSGR_5641 "putative cobyrinic acid a,c-diamide synthase"7100.0e+00
samSAM23877_1924 Cobyrinic acid A, C-diamide synthase6730.0e+00
scabSCAB70841 putative cobyrinic acid a,c-diamide synthase7070.0e+00
saceSACE_5963 cobyrinic acid a,c-diamide synthase4961.0e-174
nfarnfa40810 cobB cobyrinic acid a,c-diamide synthase4783.5e-136
mtubgi|15609985 cobyrinic acid a,c-diamide synthase [Mycobacterium tuberculosis H37Rv]4578.4e-130
paerPA1273 [gene=cobB] [prot=cobyrinic acid a,c-diamide synthase] [comment=PA1273]2057.8e-54

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

GATase_31CobB/CobQ-like glutamine amidotransferase domain258-43988.63.7e-25

CbiA1CobQ/CobB/MinD/ParA nucleotide binding domain9-19472.92.3e-20

AAA_261AAA domain83-18950.42.2e-13

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_208901593.1 cobyrinate a,c-diamide synthase [Streptomyces incarnatus] >g... 17140.0e+00
17020.0e+00
WP_177239916.1 cobyrinate a,c-diamide synthase [Streptomyces monashensis] 16960.0e+00
OIK04714.1 cobyrinic acid a,c-diamide synthase [Streptomyces monashensis] 16960.0e+00
WP_225836401.1 cobyrinate a,c-diamide synthase [Streptomyces sp. NK08204] 16950.0e+00
WP_055704326.1 cobyrinate a,c-diamide synthase [Streptomyces puniciscabiei] 16940.0e+00
WP_221334127.1 cobyrinate a,c-diamide synthase [Streptomyces sp. EAS-AB2608... 16920.0e+00
WP_208885670.1 cobyrinate a,c-diamide synthase [Streptomyces sp. PBH53] >gb... 16900.0e+00
GHH25193.1 hydrogenobyrinate a,c-diamide synthase [Streptomyces rubradiris]... 16890.0e+00
KUN04180.1 cobyrinic acid ac-diamide synthase [Streptomyces yokosukanensis] 16890.0e+00

PSORT result

LocalizationCertaintyPSORT said
membrane0.1489 Seems to have no N-terminal signal seq.