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IDSAVERM_6616 TypeCDS
From7917448 nt length912
To7916537 aa length303
Gene pI6
Definitionputative polyketide cyclase M.W (Da)32292
NotePF00753: Metallo-beta-lactamase superfamily AseI frg.G2
SignalP v.4.0Non-secretory protein | plot Categoryantibiotic production


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO5091 actIV cyclase2404.0e-79
scabSCAB72851 putative cyclase-like protein4846.0e-175
saceSACE_3955 beta-lactamase-like1403.0e-40
mtubgi|15608079 POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE) + CYCLASE/DEHYDRASE [Mycobacterium tuberculosis H37Rv]1522.1e-38

*coel, Streptomyces coelicolor A3(2); scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; mtub, Mycobacterium tuberculosis H37Rv;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

Lactamase_B1Metallo-beta-lactamase superfamily24-20775.35.9e-21

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_152866466.1 MBL fold metallo-hydrolase [Streptomyces acidicola] >gb 12081.3e-165
WP_234517538.1 MBL fold metallo-hydrolase [Streptomyces glomeratus] >lcl 12002.9e-164
WP_131563554.1 MBL fold metallo-hydrolase [Streptomyces sp. KM273126] >lcl 11993.4e-164
WP_071366576.1 MBL fold metallo-hydrolase [Streptomyces colonosanans] >gb 11891.2e-162
WP_107462691.1 MBL fold metallo-hydrolase [Streptomyces sp. MA5143a] >emb 11785.4e-161
WP_099965777.1 MBL fold metallo-hydrolase [Streptomyces sp. JV178] >gb 11785.5e-161
WP_055521515.1 MBL fold metallo-hydrolase [Streptomyces ossamyceticus] 11776.7e-161
WP_189873950.1 MBL fold metallo-hydrolase [Streptomyces bluensis] 11761.3e-160
WP_200421383.1 MBL fold metallo-hydrolase [Streptomyces sp. Y2F8-2] >dbj 11742.3e-160
WP_103839133.1 MBL fold metallo-hydrolase [Streptomyces sp. Ru72] >gb 11709.1e-160

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.2783 Seems to have no N-terminal signal seq.