| ID | SAVERM_6667 | Type | CDS |
| From | 7974140 | nt length | 3573 |
| To | 7977712 | aa length | 1190 |
| Gene | metH | pI | 4.62 |
| Definition | putative 5-methyltetrahydrofolate:homocysteine S-methyltransferase | M.W (Da) | 129516 |
| Note | PF02965: Vitamin B12 dependent methionine synthase, activation domain | AseI frg. | G2 |
| SignalP v.4.0 | Signal peptide | plot | Category | metabolism of amino acids & related molecules |
| Bacteria* | Reciprocally best hit to | Score | E-value |
| coel | SCO1657 putative methionine synthase | 2127 | 0.0e+00 |
| sgr | SGR_5847 putative 5-methyltetrahydrofolate:homocysteine S-methyltransferase | 2112 | 0.0e+00 |
| sam | SAM23877_1712 Methionine synthase | 2154 | 0.0e+00 |
| scab | SCAB73321 putative 5-methyltetrahydrofolate:homocysteine S-methyltransferase | 2120 | 0.0e+00 |
| sace | SACE_3898 putative 5-methyltetrahydrofolate:homocysteine S-methyltransferase | 1544 | 0.0e+00 |
| nfar | nfa31930 metH 5-methyltetrahydrofolate:homocysteine S-methyltransferase | 1527 | 0.0e+00 |
| mtub | gi|15609261 Probable 5-methyltetrahydrofolate--homocystein methyltransferase MetH (Methionine synthase, vitamin-B12 dependent isozyme) (MS) [Mycobacterium tuberculosis H37Rv] | 1494 | 0.0e+00 |
| cglu | gi|19552721 COG0646:Methionine synthase I (cobalamin-dependent), methyltransferase domain [Corynebacterium glutamicum] | 1422 | 0.0e+00 |
| bsub | BG13115 yitJ; methionine synthase | 146 | 8.0e-36 |
| ecoli | gi|16131845 B12-dependent methionine synthase [Escherichia coli K12] | 552 | 4.2e-158 |
| paer | PA1843 [gene=metH] [prot=methionine synthase] [comment=PA1843] | 529 | 5.3e-151 |
| Model | No. | Description | Position (aa) | Score | E-value | |
| S-methyl_trans | 1 | Homocysteine S-methyltransferase | 48-339 | 191.7 | 2e-56 | |
| Pterin_bind | 1 | Pterin binding enzyme | 374-610 | 155.7 | 1.5e-45 | |
| Met_synt_B12 | 1 | Vitamin B12 dependent methionine synthase, activation domain | 987-1188 | 139.0 | 1.8e-40 | |
| B12-binding_2 | 1 | B12 binding domain | 672-744 | 91.8 | 2.4e-26 | |
| B12-binding | 1 | B12 binding domain | 757-873 | 74.6 | 6.1e-21 |
| ID | Description | Score | E-value |
| WP_189187852.1 | methionine synthase [Streptomyces albiflavescens] >dbj | 5536 | 0.0e+00 |
| WP_028801628.1 | methionine synthase [Streptomyces sp. 142MFCol3.1] | 5527 | 0.0e+00 |
| WP_095933204.1 | methionine synthase [Streptomyces sp. Tue6028] >gb | 5512 | 0.0e+00 |
| WP_148007682.1 | methionine synthase [Streptomyces sp. me109] >lcl | 5510 | 0.0e+00 |
| WP_153291514.1 | methionine synthase [Streptomyces fagopyri] >gb | 5474 | 0.0e+00 |
| WP_168527298.1 | methionine synthase [Streptomyces sp. RPA4-2] >gb | 5465 | 0.0e+00 |
| WP_081223502.1 | methionine synthase [Streptomyces sp. M41(2017)] >gb | 5456 | 0.0e+00 |
| WP_164372487.1 | methionine synthase [Streptomyces sp. SID14446] >gb | 5447 | 0.0e+00 |
| WP_181657347.1 | methionine synthase [Streptomyces himalayensis] >lcl | 5439 | 0.0e+00 |
| WP_067365317.1 | methionine synthase [Streptomyces olivochromogenes] >gb | 5432 | 0.0e+00 |
| Localization | Certainty | PSORT said |
| Not Clear | Seems to have no N-terminal signal seq. |