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IDSAVERM_6796 TypeCDS
From8115977 nt length1233
To8117209 aa length410
GenecysG pI6.52
Definitionputative uroporphyrin-III methyltransferase M.W (Da)42796
NotePF00590: Tetrapyrrole (Corrin/Porphyrin) Methylases AseI frg.G2
SignalP v.4.0Non-secretory protein | plot Categorymetabolism of coenzymes & prosthetic groups

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO1553 putative uriporphyrin-III methyltransferase6810.0e+00
sgrSGR_5984 putative uroporphyrin-III methyltransferase6300.0e+00
samSAM23877_1607 uroporphyrin-III methyltransferase6860.0e+00
scabSCAB74471 putative uroporphyrin-III methyltransferase6710.0e+00
saceSACE_5957 uroporphyrin-III C-methyltransferase4302.0e-150
nfarnfa40770 cysG uroporphyrinogen III methylase4845.7e-138
mtubgi|57117027 POSSIBLE MULTIFUNCTIONAL ENZYME SIROHEME SYNTHASE CYSG: UROPORPHYRIN-III C-METHYLTRANSFERASE (UROGEN III METHYLASE) (SUMT) (UROPORPHYRINOGEN III METHYLASE) (UROM) + PRECORRIN-2 OXIDASE + FERROCHELATASE [Mycobacterium tuberculosis H37Rv]4646.1e-132
cglugi|19553202 COG0007:Uroporphyrinogen-III methylase [Corynebacterium glutamicum]2614.2e-71
bsubBG13380 ylnD; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]1954.6e-51
ecoligi|16131246 siroheme synthase, catalyses four reactions between uroporphyrinogen III and siroheme [Escherichia coli K12]2123.2e-56
paerPA2611 [gene=cysG] [prot=siroheme synthase] [comment=PA2611]2064.1e-54

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

TP_methylase1Tetrapyrrole (Corrin/Porphyrin) Methylases170-381159.78.5e-47

NAD_binding_71Putative NAD(P)-binding11-11867.79.3e-19

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_189187964.1 uroporphyrinogen-III C-methyltransferase [Streptomyces albif... 14960.0e+00
WP_075027594.1 uroporphyrinogen-III C-methyltransferase [Streptomyces mirab... 14940.0e+00
WP_067365813.1 uroporphyrinogen-III C-methyltransferase [Streptomyces olivo... 14910.0e+00
WP_097226419.1 uroporphyrinogen-III C-methyltransferase [Streptomyces sp. O... 14900.0e+00
WP_053759791.1 MULTISPECIES: uroporphyrinogen-III C-methyltransferase [Stre... 14890.0e+00
WP_081223401.1 uroporphyrinogen-III C-methyltransferase [Streptomyces sp. M... 14860.0e+00
WP_190196841.1 uroporphyrinogen-III C-methyltransferase [Streptomyces djaka... 14860.0e+00
WP_151468424.1 uroporphyrinogen-III C-methyltransferase [Streptomyces triti... 14860.0e+00
WP_095855744.1 uroporphyrinogen-III C-methyltransferase [Streptomyces sp. A... 14850.0e+00
WP_143601083.1 MULTISPECIES: uroporphyrinogen-III C-methyltransferase [uncl... 14850.0e+00

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.2016 Seems to have no N-terminal signal seq.