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IDSAVERM_6840 TypeCDS
From8164005 nt length2538
To8166542 aa length845
GenerelA pI9.81
DefinitionppGpp synthetase M.W (Da)93742
NotePF04607: Region found in RelA / SpoT proteins AseI frg.G2
SignalP v.4.0Non-secretory protein | plot Categorymetabolism of nucleotides & nucleic acids


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO1513 relA GTP pyrophosphokinase15650.0e+00
sgrSGR_6022 putative ppGpp synthetase15100.0e+00
samSAM23877_1564 GTP pyrophosphokinase15870.0e+00
scabSCAB74961 putative ppGpp synthetase15200.0e+00
saceSACE_2028 GTP pyrophosphokinase10450.0e+00
nfarnfa36840 relA ppGpp synthetase9910.0e+00
mtubgi|15609720 PROBABLE GTP PYROPHOSPHOKINASE RELA (ATP:GTP 3'-PYROPHOSPHOTRANSFERASE) (PPGPP SYNTHETASE I) ((P)PPGPP SYNTHETASE) (GTP DIPHOSPHOKINASE) [Mycobacterium tuberculosis H37Rv]10030.0e+00
cglugi|19552864 COG0317:Guanosine polyphosphate pyrophosphohydrolases/synthetases [Corynebacterium glutamicum]9000.0e+00
bsubBG12665 relA; GTP pyrophosphokinase [EC:2.7.6.5]6530.0e+00
ecoligi|16131521 (p)ppGpp synthetase II; also guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [Escherichia coli K12]5323.1e-152
paerPA0934 [gene=relA] [prot=GTP pyrophosphokinase] [comment=PA0934]5064.3e-144

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

HD_41HD domain127-274173.72e-51

RelA_SpoT1Region found in RelA / SpoT proteins334-443128.81.1e-37

TGS1TGS domain501-56077.07.6e-22

ACT_41ACT domain759-83564.01.4e-17

ACT1ACT domain765-82846.32.5e-12

HD1HD domain146-24342.56.2e-11

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_153291653.1 RelA/SpoT family protein [Streptomyces fagopyri] >gb 41170.0e+00
WP_119102493.1 RelA/SpoT family protein [Streptomyces sporangiiformans] >lc... 41010.0e+00
WP_148007804.1 RelA/SpoT family protein [Streptomyces sp. me109] >lcl 40940.0e+00
WP_138047803.1 RelA/SpoT family protein [Streptomyces montanus] >lcl 40520.0e+00
WP_152867826.1 RelA/SpoT family protein [Streptomyces acidicola] >gb 40510.0e+00
WP_131564688.1 RelA/SpoT family protein [Streptomyces sp. KM273126] >lcl 40410.0e+00
WP_189936557.1 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosp... 40330.0e+00
WP_143635413.1 RelA/SpoT family protein [Streptomyces sp. IB201691-2A2] >lc... 40260.0e+00
WP_151482595.1 RelA/SpoT family protein [Streptomyces albicerus] 40220.0e+00
WP_200421212.1 RelA/SpoT family protein [Streptomyces sp. Y2F8-2] >dbj 40170.0e+00

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.3870 Seems to have no N-terminal signal seq.